171017-31-5

Basic information

• Product Name: 5-[4-(Benzyl-tert-butoxycarbonyl-amino)-4-oxo-but-(Z)-ylidene]-3-methyl-2-oxo-2,5-dihydro-pyrrole-1-carboxylic acid tert-butyl ester
• Synonyms: 5-[4-(Benzyl-tert-butoxycarbonyl-amino)-4-oxo-but-(Z)-ylidene]-3-methyl-2-oxo-2,5-dihydro-pyrrole-1-carboxylic acid tert-butyl ester
• CAS NO: 171017-31-5
• Molecular Weight: 470.566
• Mol File: 171017-31-5.mol

Chemical Properties

• CAS DataBase Reference: 5-[4-(Benzyl-tert-butoxycarbonyl-amino)-4-oxo-but-(Z)-ylidene]-3-methyl-2-oxo-2,5-dihydro-pyrrole-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[4-(Benzyl-tert-butoxycarbonyl-amino)-4-oxo-but-(Z)-ylidene]-3-methyl-2-oxo-2,5-dihydro-pyrrole-1-carboxylic acid tert-butyl ester(171017-31-5)
• EPA Substance Registry System: 5-[4-(Benzyl-tert-butoxycarbonyl-amino)-4-oxo-but-(Z)-ylidene]-3-methyl-2-oxo-2,5-dihydro-pyrrole-1-carboxylic acid tert-butyl ester(171017-31-5)

Safety Data

• Hazardous Substances Data: 171017-31-5(Hazardous Substances Data)

Upstream product

• 171017-17-7 N-benzyl-N-tert-butoxycarbonyl-4-oxo-butanamide 
• 181635-62-1 (1-tert-butoxycarbonyl-3-methyl-3-pyrrolin)-5-yl-phosphonic acid diethyl ester 
• 2555-05-7 3-methyl-2-pyrrolidinone 
• 24424-99-5 di-tert-butyl dicarbonate 
• 100-46-9 benzylamine 
• 171017-20-2 tert-butyl 3-methyl-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate 
• 171017-19-9 tert-butyl 3-methyl-2-oxo-3-(phenylselanyl)-1-pyrrolidinecarboxylate 
• 1026061-10-8 3-Methyl-2-trimethylsilanyloxy-pyrrole-1-carboxylic acid tert-butyl ester 
• 171017-18-8 tert-butyl 3-methyl-2-oxo-1-pyrrolidine-carboxylate 
• 171017-16-6 N-benzyl-N-tert-butoxycarbonyl-4-pentenamide 
• 58170-50-6 pent-4-enoic acid benzylamide 

Relevant articles and documents

Synthesis of azaspiro[4.5]decane systems by oxidative cyclization of olefinic precursors

The synthesis of 6-benzyloxycarbonyl-1-oxa-6-azaspiro[4.5]decan-2-one (17) and 6-benzyloxycarbonyl-1,6-diazaspiro[4.5]decan-2-one (18) from the D,L-pipecolic acid derivative 10, is described. The synthesis of (±)-6- benzyl-3-methyl-1,6-diazaspiro[4.5]dec-3-ene-2,7-dione (29), the spiro structural unit of (±)-pandamarine (8) has been achieved by oxidative cyclization of the (Z) and (E) isomers of 5-(N-benzyl-4- carboxamidobutylidene)-3-methyl-3-pyrrolin-2-one (25) and (26). The stereoselectivity obtained in the intramolecular cyclization process has also been discussed.

Synthesis of α,β-Unsaturated Spirolactams by Intramolecular Cyclization of Endocyclic N-Acyliminium Ions

The synthesis of (+/-)-6-benzyl-3-methyl-3-en-1,6-diazaspirodecane-2,7-dione (18), the spiro moiety of (+/-)-pandamarine has been achieved by oxidative cyclization of the (Z) and (E) isomers of 5-(N-benzyl-4-carboxamido-butylidene)-3-methyl-3-en-pyrrolin-2-one (15a) and (15b).The stereoselectivity exhibited in the intramolecular cyclization by both butylidene precursors has also been discussed.