17174-98-0

Basic information

• Product Name: 2-CYANOBENZAMIDE
• Synonyms: 2-cyano-benzamid;o-cyano-benzamid;TIMTEC-BB SBB007653;O-CYANOBENZAMIDE;PHTHALAMIC NITRILE;2-CYANOBENZAMIDE;Benzamide, 2-cyano- (9CI);ORTHO-CYANOBENZAMIDE
• CAS NO: 17174-98-0
• Molecular Formula: C₈H₆N₂O
• Molecular Weight: 146.15
• EINECS: 241-224-0
• Product Categories: AMIDE;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
• Mol File: 17174-98-0.mol
• Article Data: 12

Chemical Properties

• Melting Point: 172-173°C
• Boiling Point: 265.75°C (rough estimate)
• Flash Point: 160.3°C
• Appearance: /
• Density: 1.2312 (rough estimate)
• Vapor Pressure: 8E-05mmHg at 25°C
• Refractive Index: 1.4900 (estimate)
• Storage Temp.: 2-8°C
• PKA: 15.23±0.50(Predicted)
• CAS DataBase Reference: 2-CYANOBENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYANOBENZAMIDE(17174-98-0)
• EPA Substance Registry System: 2-CYANOBENZAMIDE(17174-98-0)

Safety Data

• Statements: 20/21/22-36
• Safety Statements: 22-36/37/39-26
• RIDADR: 3276
• RTECS: CV2483500
• TSCA: Yes
• PackingGroup: III
• Hazardous Substances Data: 17174-98-0(Hazardous Substances Data)

Usage

General Description

2-Cyanobenzamide is a chemical compound with the formula C8H6N2O. It is a benzamide derivative with a cyano group attached to the benzene ring. 2-CYANOBENZAMIDE is a white solid at room temperature, and it is sparingly soluble in water but soluble in organic solvents. 2-Cyanobenzamide has been widely used as a building block in organic synthesis, particularly in the production of pharmaceuticals and agrochemicals. It is also used as a precursor in the synthesis of various organic compounds due to its reactivity and versatility. Additionally, 2-Cyanobenzamide has been studied for its potential biological and pharmacological activities.

InChI:InChI=1/C8H6N2O/c9-5-6-3-1-2-4-7(6)8(10)11/h1-4H,(H2,10,11)

Upstream product

• 88-96-0 phthalamide 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 
• 643-79-8 o-phthalic dicarboxaldehyde 
• 3839-22-3 2-cyanobenzoic acid 
• 91-15-6 phthalonitrile 
• 136918-14-4 phthalimide 
• 88-97-1 phthalamic acid 
• 64148-19-2 2-dichloromethyl-benzonitrile 
• 6587-24-2 methyl 2-cyanobenzoate 

Downstream Products

• 52059-77-5 2-(2-oxo-1,3,4-oxathiazol-5-yl)benzonitrile 
• 3839-22-3 2-cyanobenzoic acid 
• 3317-67-7 cobalt(II) phthalocyanine 
• 132-16-1 iron(II) phthalocyanine 
• 14566-41-7 RuCl(C₃₂H₁₆N₈)*C₈H₆N₂O 
• 1186372-05-3 1-(2-cyanobenzoyl)-3-(9H-fluoren-9-yl)-urea 
• 1126634-14-7 2-(4-(chloromethyl)oxazol-2-yl)benzonitrile 
• 14055-02-8 nickel(II) phthalocyanine 
• 147-14-8 copper phthalocyanine 
• 88636-64-0 tert-butyl 2-cyanobenzoate 
• 6525-45-7 2-cyano-benzoic acid ethyl ester 
• 6587-24-2 methyl 2-cyanobenzoate 
• 88-97-1 phthalamic acid 
• 88-99-3 benzene-1,2-dicarboxylic acid 

Relevant articles and documents

Method for preparing derivatives of benzamide under microwave condition in aqueous phase

The invention discloses a method for preparing derivatives of benzamide under a microwave condition in an aqueous phase. A coupling reaction is carried out between substituted benzoic acid and amine under the microwave condition in the aqueous phase. The method for preparing the derivatives of benzamide is environmentally friendly, easy and convenient to operate, safe, low in cost and efficient. Compared with the prior art, the method can be applicable to a large number of functional groups, is high in yield, produces fewer by-products, and further is easy to operate, safe, low in cost and environmentally friendly. A formula is shown in the description.

Magnetic Nanoparticle-Supported Cu–NHC Complex as an Efficient and Recoverable Catalyst for Nitrile Hydration

Magnetic nanoparticles supported N-heterocyclic carbene–Cu complex was prepared and authenticated by FT-IR, SEM, EDX, VSM, powder-XRD. The catalytic activity of these magnetically retrievable NPs was investigated for hydration of nitriles as the simplest route for the synthesis of amides in an atom-economical manner. A wide range of nitriles containing various functional groups such as olefin, aldehyde, nitro, carboxylic acid was examined in this transformation to generate their corresponding amides in the aqueous medium. The immobilized catalyst was easily recovered using an external magnet and reused for six times without significant loss of its catalytic activity. Graphical Abstract: [Figure not available: see fulltext.].