17249-78-4

Basic information

• Product Name: 2,3,4-TRICHLOROTHIOPHENE
• Synonyms: 2,3,4-TRICHLOROTHIOPHENE;3-5g
• CAS NO: 17249-78-4
• Molecular Formula: C₄HCl₃S
• Molecular Weight: 187.47474
• Mol File: 17249-78-4.mol

Chemical Properties

• Boiling Point: 212°Cat760mmHg
• Flash Point: 105.6°C
• Appearance: /
• Density: 1.633g/cm³
• Vapor Pressure: 0.257mmHg at 25°C
• Refractive Index: 1.601
• CAS DataBase Reference: 2,3,4-TRICHLOROTHIOPHENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3,4-TRICHLOROTHIOPHENE(17249-78-4)
• EPA Substance Registry System: 2,3,4-TRICHLOROTHIOPHENE(17249-78-4)

Safety Data

• Hazardous Substances Data: 17249-78-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2,3,4-Trichlorothiophene is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2,3,4-Trichlorothiophene serves as an essential intermediate for the production of various agrochemicals, contributing to the development of effective pest control agents and other agricultural products.
Used in Dye and Pigment Production:
2,3,4-Trichlorothiophene is utilized as a starting material in the production of dyes and pigments, enabling the creation of a wide range of colorants for various applications, including textiles, plastics, and printing inks.
Used in Organic Compound Synthesis:
Due to its reactivity, 2,3,4-Trichlorothiophene is employed in the synthesis of other organic compounds, expanding its applications across various industries that rely on organic chemistry for product development.
It is crucial to handle 2,3,4-Trichlorothiophene with care, as it can be toxic and harmful if not used properly. Exposure to this chemical may cause irritation to the eyes, skin, and respiratory system, emphasizing the need for proper safety measures during its use in industrial applications.

InChI:InChI=1/C4HCl3S/c5-2-1-8-4(7)3(2)6/h1H

Upstream product

• 188290-36-0 thiophene 
• 672308-95-1 2,2,3,4,5-pentachloro-tetrahydro-thiophene 
• 6012-97-1 2,3,4,5-tetrachlorothiophene 
• 26020-48-4 3,4,5-trichlorothiophene-2-carboxylic acid 

Downstream Products

• 65434-11-9 2-acetyl-3,4,5-trichlorothiophene 
• 26020-48-4 3,4,5-trichlorothiophene-2-carboxylic acid 
• 38458-33-2 3,4-dichloro-2,5-thiophenedicarboxylic acid 
• 17249-76-2 3,4-dichlorothiophene 
• 6012-97-1 2,3,4,5-tetrachlorothiophene 

Relevant articles and documents

A simple protocol for Cu-catalyzed protodecarboxylation of (hetero)aromatic carboxylic acids

A simple and practical protodecarboxylation of o-nitrobenzoic acids as well as heteroaromatic carboxylic acids with various substituents via using CuI/Et3N has been established. This transformation provides a viable and low-cost approach to generating previously unavailable substituted arenes from readily accessible aryl carboxylic acids as the starting materials.

Decarboxylative homocoupling of (hetero)aromatic carboxylic acids

A variety of hetero(aromatic) carboxylic acids are shown to undergo decarboxylative homocoupling, mediated by a Pd/Ag system. This novel methodology for the synthesis of symmetrical biaryls avoids the use of haloarenes and organometallic compounds as starting materials.

Silver-catalyzed protodecarboxylation of heteroaromatic carboxylic acids

[Chemical Equation Presented] A simple and highly efficient protodecarboxylation procedure for a variety of heteroaromatic carboxylic acids catalyzed by Ag2CO3 and AcOH in DMSO is described. This methodology can also perform the selective monoprotodecarboxylation of several aromatic dicarboxylic acids.

2-Heterocyclic-1,3-bis(1H-1,2,4-triazol-1-yl)-propan-2-ols as antifungal agents

Compounds of the formula STR1 wherein R is thienyl, mono-, di- and trihalothienyl, furyl, 2-benzothiazolyl, pyridyl or chloropyridyl and their pharmaceutically acceptable salts are useful agents for combating fungal infections in animals, including humans.

Sulfonation of aromatic compounds in the presence of solvents

A process for the sulfonation of aromatic compounds wherein an aromatic substance consisting of one or more aromatic compounds susceptible to the action of sulfur trioxide is formed into a reactant by admixture with one or more organic liquids, substantially inert to sulfur trioxide under the conditions of the process, which reactant is brought to boiling at a temperature not greater than 100° C under a pressure of from 0.1 mm Hg to atmospheric pressure, gaseous sulfur trioxide is introduced thereinto thereby causing it to continue to boil, the component or components of the reactant thus volatilized is or are reconverted to liquid in a heat-exchanger and recycled to the reaction chamber, and the pressure in the reaction chamber and the rate at which the gaseous sulfur trioxide is introduced into the reactant are controlled so as to ensure that there is always present in the reaction chamber an amount of volatilizable matter exceeding that amount volatilizable by the heat of reaction of the aromatic substance present in the reaction chamber with the gaseous sulfur trioxide in contact with said aromatic substance and that the temperature of the reaction mixture is a temperature of 100° C or below.