17802-02-7Relevant articles and documents
ANTIBIOTIC COMPOUNDS
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Page/Page column 154, (2018/03/25)
The present invention relates to antibiotic compounds of formula (I), to compositions containing these compounds and to methods of treating bacterial diseases and infections using the compounds. The compounds find application in the treatment of infection with, and diseases caused by, Gram-positive and/or Gram-negative bacteria, and in particular in the treatment of infection with, and diseases caused by, Neisseria gonorrhoeae.
CONDENSED HETEROCYCLIC COMPOUND
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Paragraph 0381-0383, (2017/11/08)
A compound represented by the general formula (I) [R1 represents a C1-6 alkyl group, a halogen atom, or the like; A represents a phenylene group, or the like; X represents —CH(R3)—, —O—, —NH—, or the like; Y represents —O—, —NH—, —N═, or —S—; . . . represents a single bond or double bond; n represents 1 to 3; R2 represents a C1-6 alkyl group, a C1-6 alkoxy group, or the like; and R3 represents hydrogen atom, a C1-6 alkyl group, or the like], or a salt thereof which has a blood LDL cholesterol-reducing action, and is useful as an active ingredient of medicaments.
PYRAZOLE COMPOUNDS
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Page/Page column 29, (2010/04/30)
The present invention relates to wherein each symbol is as defined in the specification. The compound has a superior mineralocorticoid receptor antagonistic action and is useful as an agent for the prophylaxis or treatment of a disease or condition mediated by the mineralocorticoid receptor activation.
INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
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Page/Page column 47-48, (2010/12/01)
Compounds of formula I wherein a, R1, R2, R3, R4, R5 and R6 are defined herein, are useful as inhibitors of HIV replication.
INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
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Page/Page column 64, (2009/06/27)
Compounds of formula (I): wherein R4, R6 and R7 are defined herein, are useful as inhibitors of HIV replication.
INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
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Page/Page column 73-74, (2009/06/27)
Compounds of formula (I): wherein c, X, Y, R2, R4 and R5 are defined herein, are useful as inhibitors of HIV replication.
INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
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Page/Page column 70-71, (2009/06/27)
The present invention relates to compounds of formula (I) wherein c, X, Y, R2, R3, R4 and R6 are as defined herein, compositions and uses thereof for treating human immunodeficiency virus (HIV) infection. In particular, the present invention provides novel inhibitors of HIV integrase, pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HIV infection
INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION
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Page/Page column 77-78, (2009/06/27)
Compounds of formula I : wherein c, R2, R3, R4, R5, R6, R7 and R8 are defined herein, are useful as inhibitors of HIV replication.
REACTION OF AROMATIC COMPOUNDS WITH NUCLEOPHILIC REAGENTS IN LIQUID AMMONIA. XIII. DIRECTION OF HYDROXYLATION OF 2-HALONITROBENZENES BY POTASSIUM HYDROXIDE
Malykhin, E. V.,Kolesnichenko, G. A.,Shteingarts, V. D.
, p. 1149 - 1152 (2007/10/02)
The reaction of 2-fluoronitrobenzene with potassium hydroxide and molecular oxygen in liquid ammonia at -33 deg C gave 2-nitrophenol.In contrast to 2-fluoronitrobenzene, both the halogen and hydrogen in the ortho and para positions to the nitro group are replaced in the reactions of 2-chloro- and 2-bromonitrobenzenes, KOH, and O2.In the case of 2-bromonitrobenzene, there is significant formation of a compound, formally corresponding to reductive dehalogenation (nitrobenzene and its hydroxylation product, 4-nitrophenol) and bromination of the nitrophenols formed in the position to the hydroxy group.