611-07-4

Basic information

• Product Name: 5-Chloro-2-nitrophenol
• Synonyms: 5-chloro-2-nitrophenol;5-Chlor-2-nitrophenol;2-Nitro-5-chlorophenol;5-Chloro-2-nitrophenol 95+%;Phenol,5-chloro-2-nitro-;4-Chloro-2-hydroxynitrobenzene;5-Chloro-2-nitrobenzenol;6-Nitro-3-chlorophenol
• CAS NO: 611-07-4
• Molecular Formula: C₆H₄ClNO₃
• Molecular Weight: 173.55
• EINECS: 210-249-9
• Mol File: 611-07-4.mol
• Article Data: 25

Chemical Properties

• Melting Point: 41°C
• Boiling Point: 247.6 °C at 760 mmHg
• Flash Point: 103.5 °C
• Appearance: /
• Density: 1.4914 (rough estimate)
• Vapor Pressure: 0.0161mmHg at 25°C
• Refractive Index: 1.5810 (estimate)
• Storage Temp.: Room temperature.
• PKA: 6.08±0.13(Predicted)
• CAS DataBase Reference: 5-Chloro-2-nitrophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloro-2-nitrophenol(611-07-4)
• EPA Substance Registry System: 5-Chloro-2-nitrophenol(611-07-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 611-07-4(Hazardous Substances Data)

Usage

General Description

5-Chloro-2-nitrophenol is a chemical compound with the formula C6H4ClNO3. It is a yellow crystalline solid that is used in the manufacturing of dyes, pharmaceuticals, and agricultural chemicals. It is also used as an intermediate in the production of other organic compounds. 5-Chloro-2-nitrophenol is a hazardous substance and can cause irritation to the skin, eyes, and respiratory system. It is important to handle and store this chemical with proper safety precautions to avoid any potential health risks.

InChI:InChI=1/C6H4ClNO3/c7-4-1-2-5(8(10)11)6(9)3-4/h1-3,9H

Upstream product

• 100-00-5 4-chlorobenzonitrile 
• 7732-18-5 water 
• 108-42-9 3-chloro-aniline 
• 108-43-0 3-monochlorophenol 
• 7697-37-2 nitric acid 
• 64-17-5 ethanol 
• 7664-93-9 sulfuric acid 
• 64-19-7 acetic acid 
• 1635-61-6 5-chloro-2-nitroaniline 
• 28373-39-9 2-(3-chlorophenoxy)pyridine 
• 6627-53-8 1-chloro-3-methoxy-4-nitrobenzene 
• 119-76-6 N,N'-(4-nitro-m-phenylene)-bis-acetamide 
• 5131-58-8 2,4-diaminonitrobenzene 
• 611-06-3 2,4-dichloronitrobenzene 

Downstream Products

• 29604-25-9 4-chloro-2-ethoxy-1-nitrobenzene 
• 1706-82-7 3-chloro-2,4,6-trinitro-phenol 
• 54715-57-0 5-chloro-2,4-dinitrophenol 
• 858854-93-0 4,6-dibromo-3-chloro-2-nitro-phenol 
• 54715-56-9 3-chloro-2,6-dinitro-phenol 
• 28443-50-7 2-amino-5-chlorophenol 
• 16323-09-4 N-(4-chloro-2-hydroxyphenyl)acetamide 
• 40422-90-0 4-chloro-1-nitro-2-(propan-2-yloxy)benzene 
• 907587-43-3 methyl 4-[(5-chloro-2-nitrophenoxy)methyl]benzoate 
• 6627-53-8 1-chloro-3-methoxy-4-nitrobenzene 

Relevant articles and documents

Method for hydrolyzing nitroaniline substances into phenol

The invention discloses a method for hydrolyzing nitroaniline substances into phenol. The method comprises the following steps: mixing the nitroaniline substances, a catalyst and inorganic base whichare used as raw materials with water used as a solvent, adding the mixture to a reactor, sealing the reactor, and heating the reactor to 100-190 DEG C for a reaction for 2-8 h; cooling an obtained reaction solution to room temperature, then, adjusting pH to 1-2, and washing and drying obtained precipitates to obtain the product, namely, nitrophenol substances. The nitrophenol substances are synthesized with the method, the utilization rate of the raw materials is high, expensive catalysts are not used, emission of three wastes is reduced, the production cost is reduced, and the product has high purity, high yield and good industrial application values.

A ortho-nitro phenol and its derivative synthesis method (by machine translation)

The invention relates to a method for the synthesis of organic compounds, in the existing technology of O-nitrophenol strong acid used in the synthesis process of the serious problem of environmental pollution and the synthesis step longer more complicated problem, the invention provides a ortho-nitro phenol and synthetic method of derivative thereof, proceeding by the phenol compound, synthesis of 2 - (phenoxy) pyridine, the obtained product, catalyst, tert-butyl nitrite, organic solvent and adding sealing in the pressure containers, in oil bath heating 50 - 100 °C, reaction 10 - 30 hours, to obtain 2 - (2 - nitrobenzene) ethoxy pyridine; re-processing by the ortho-nitro phenol and its derivatives; the method is simple, high-efficiency. (by machine translation)

Spiro aryl phosphorus oxide or sulfide

The invention discloses a spiro aryl phosphorus oxide or sulfide as ALK inhibitor, and in particular discloses a compound shown in a formula (I) as an ALK inhibitor or a pharmaceutically acceptable salt thereof.