180736-79-2Relevant articles and documents
Syntheses of new 9- and 13-methylene isomers of retinal
Laurent,Prat,Valla,Andriamialisoa,Giraud,Labia,Potier
, p. 7221 - 7224 (2000)
Syntheses of new 9- and 13-methylene isomers of retinal via the '9-methylene-C-18 ketone' 1 or 'C-18 ketone' 2 are reported. (C) 2000 Published by Elsevier Science Ltd.
Stereoselective synthesis of 9-methylene-13-demethyl analogs of natural retinoids
Valla,Prat,Laurent,Andriamialisoa,Cartier,Labia,Potier
, p. 3219 - 3223 (2007/10/03)
9-Methylene-13-demethyl analogs of retinol, retinal and retinoic acid, methyl ester were synthesised via new synthons β-methylenealdehydes.
Stereoselective synthesis of 13Z retinoic acids via β-methylenealdehydes as synthons
Valla, Alain,Andriamialisoa, Zo,Giraud, Michel,Prat, Virginie,Laurent, Alain,Potier, Pierre
, p. 9235 - 9237 (2007/10/03)
A stereoselective synthesis of 13Z retinoic acids via β-methylenealdehydes is described. In methylene-de-oxo-bisubstitution reactions (Knoevenagel, Stobbe, etc.), these new synthons produce stereoselectively E olefins. Hence, a synthesis of 13Z retinoic acids is described, via a stereospecific monodecarboxylation of carboxy-14-retinoic acids.