2-[3-(2,2-dimethoxy-ethyl)-buta-1,3-dienyl]-1,3,3-trimethylcyclohexene

Base Information

• Chemical Name: 2-[3-(2,2-dimethoxy-ethyl)-buta-1,3-dienyl]-1,3,3-trimethylcyclohexene
• CAS No.: 180736-79-2
• Molecular Formula: C₁₇H₂₈O₂
• Molecular Weight: 264.408
• Mol file: 180736-79-2.mol

Synonyms:2-[3-(2,2-dimethoxy-ethyl)-buta-1,3-dienyl]-1,3,3-trimethylcyclohexene

Chemical Property of 2-[3-(2,2-dimethoxy-ethyl)-buta-1,3-dienyl]-1,3,3-trimethylcyclohexene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[3-(2,2-dimethoxy-ethyl)-buta-1,3-dienyl]-1,3,3-trimethylcyclohexene

There total 4 articles about 2-[3-(2,2-dimethoxy-ethyl)-buta-1,3-dienyl]-1,3,3-trimethylcyclohexene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

Methyltriphenylphosphonium bromide (1779-49-3) + 5,5-dimethoxy-1-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-1-en-3-one (85458-25-9) → 2-[3-(2,2-dimethoxy-ethyl)-buta-1,3-dienyl]-1,3,3-trimethylcyclohexene (180736-79-2)

Guidance literature:

With potassium tert-butylate; In cyclohexane;

DOI:10.1016/S0040-4039(99)01963-2

Reference yield:

(E)-β-ionone (79-77-6,14901-07-6) → 2-[3-(2,2-dimethoxy-ethyl)-buta-1,3-dienyl]-1,3,3-trimethylcyclohexene (180736-79-2)

Guidance literature:

Multi-step reaction with 3 steps

1: NaOMe / pentane

2: H₂SO₄

3: t-BuOK / cyclohexane

With sulfuric acid; potassium tert-butylate; sodium methylate; In cyclohexane; pentane; 3: Wittig reaction;

DOI:10.1081/SCC-100106030

Reference yield:

1-hydroxy-5-(2,6,6-trimethyl-cyclohex-1-enyl)-penta-1,4-dien-3-one (180736-86-1) → 2-[3-(2,2-dimethoxy-ethyl)-buta-1,3-dienyl]-1,3,3-trimethylcyclohexene (180736-79-2)

Guidance literature:

Multi-step reaction with 2 steps

1: H₂SO₄

2: t-BuOK / cyclohexane

With sulfuric acid; potassium tert-butylate; In cyclohexane; 2: Wittig reaction;

DOI:10.1081/SCC-100106030

upstream raw materials:

Methyltriphenylphosphonium bromide

5,5-dimethoxy-1-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-1-en-3-one

(trimethylsilyl)methylmagnesium chloride

(E)-β-ionone

Downstream raw materials:

7-methylene-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,8-trien-1-ol

7-methylene-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,8-trienoic acid methyl ester

2-[(2E,4E,6E)-1,5-Dimethyl-7-(2,6,6-trimethyl-cyclohex-1-enyl)-hepta-2,4,6-trien-(E)-ylidene]-malonic acid monomethyl ester

acide-2-carboxy-3,7-dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2E,4E,6E,8E-tetraenoique