183266-61-7 Usage
Uses
Used in Pharmaceutical Industry:
1-TRIFLUOROMETHYLACETYLBENZOTRIAZOLE& is used as a reactant for defluorination dimerization reactions mediated by single electron transfer (SET) reagent, sodium naphthalenide. This reaction is crucial in the synthesis of various pharmaceutical compounds.
Used in Cancer Research:
1-TRIFLUOROMETHYLACETYLBENZOTRIAZOLE& is used as a component in the preparation of scaffolds endowed with anticancer activity against breast cancer cells. Its unique structure contributes to the development of potential therapeutic agents.
Used in Peptide Synthesis:
1-TRIFLUOROMETHYLACETYLBENZOTRIAZOLE& is used as a building block in the synthesis of aspartylglycine dipeptide mimetics. These mimetics have potential applications in the development of drugs targeting various diseases, including neurodegenerative disorders.
Used in Organic Synthesis:
1-TRIFLUOROMETHYLACETYLBENZOTRIAZOLE& is used as a coupling agent in reactions for the synthesis of carboxylic acid esters. Its reactivity and stability make it a valuable component in the development of new organic compounds.
Used in Trifluoroacetylation Reactions:
1-TRIFLUOROMETHYLACETYLBENZOTRIAZOLE& is used as a trifluoroacetylating agent in various chemical reactions. Its ability to introduce a trifluoroacetyl group into a molecule can enhance the properties of the resulting compound, such as increasing its lipophilicity and metabolic stability.
Check Digit Verification of cas no
The CAS Registry Mumber 183266-61-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,3,2,6 and 6 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 183266-61:
(8*1)+(7*8)+(6*3)+(5*2)+(4*6)+(3*6)+(2*6)+(1*1)=147
147 % 10 = 7
So 183266-61-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H4F3N3O/c9-8(10,11)7(15)14-6-4-2-1-3-5(6)12-13-14/h1-4H
183266-61-7Relevant articles and documents
Ester compounds, liquid crystal compositions and liquid crystal display devices
-
, (2008/06/13)
Liquid crystalline compounds suitable for driving at a low voltage and at a wide temperature range, and suitable for high speed response, liquid crystal compositions comprising the compound, and liquid crystal display devices comprising the liquid crystal
A simple and efficient synthesis of an Asp-Gly dipeptide mimetic
Ndungu, John M.,Gu, Xuyuan,Gross, Dustin E.,Ying, Jinfa,Hruby, Victor J.
, p. 3245 - 3247 (2007/10/03)
Alkylation of Nα-Boc protected aspartic acid with allyl bromide in the presence of lithium bis(trimethylsilyl)amide (LHMDS) and hexamethylphosphoramide (HMPA) afforded chiral β-allyl substituted aspartic acid in good yields. After deprotection of the Nα-Boc group and reprotection as a trifluoroacetamide, the terminal alkene was oxidized to an aldehyde. The aldehyde was then coupled with L-cysteine through a cascade three-bond formation process to afford aspartic acid-glycine bicyclic dipeptide mimetics.
ESTER COMPOUNDS, LIQUID CRYSTAL COMPOSITIONS AND LIQUID CRYSTAL DISPLAY DEVICES
-
, (2008/06/13)
The present invention is to provide liquid crystalline compounds suitable for driving at a low voltage and at a wide temperature range, and are suitable for high speed response, to provide liquid crystal compositions comprising the compound, and to provid