185-69-3 Usage
Uses
Used in Pharmaceutical Industry:
1-Azaspiro[2.5]octane is used as a key intermediate in the synthesis of pharmaceuticals for its potential as a selective norepinephrine reuptake inhibitor. This application is crucial for the development of treatments targeting depression, anxiety, and attention-deficit hyperactivity disorder, where modulation of norepinephrine levels can significantly impact patient outcomes.
Used in Agrochemical Industry:
In the agrochemical sector, 1-Azaspiro[2.5]octane serves as a vital component in the creation of agrochemicals, contributing to the development of effective pest control agents and other agricultural products that enhance crop protection and yield.
Used in Organic Chemistry Research:
1-Azaspiro[2.5]octane is utilized as a chiral ligand in organic chemistry, playing a critical role in asymmetric synthesis and catalysis. Its unique structural properties allow for the creation of enantioselective reactions, which are essential for producing chiral molecules with specific biological activities.
Used in the Synthesis of Complex Organic Molecules:
As a building block, 1-Azaspiro[2.5]octane is employed in the assembly of complex organic molecules, facilitating the construction of intricate molecular architectures with potential applications in material science, medicinal chemistry, and other specialized fields. Its ability to be incorporated into larger structures broadens its utility and impact on the advancement of novel compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 185-69-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,8 and 5 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 185-69:
(5*1)+(4*8)+(3*5)+(2*6)+(1*9)=73
73 % 10 = 3
So 185-69-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H13N/c1-2-4-7(5-3-1)6-8-7/h8H,1-6H2
185-69-3Relevant articles and documents
Modular, One-Pot, Sequential Aziridine Ring Opening-SNAr Strategy to 7-, 10-, and 11-Membered Benzo-Fused Sultams
Loh, Joanna K.,Asad, Naeem,Samarakoon, Thiwanka B.,Hanson, Paul R.
, p. 9926 - 9941 (2015/11/03)
The generation of common and stereochemically rich medium-sized benzo-fused sultams via complementary pairing of heretofore-unknown (o-fluoroaryl)sulfonyl aziridine building blocks with an array of amino alcohols/amines in a modular one-pot, sequential protocol using an aziridine ring opening and intramolecular nucleophilic aromatic substitution is reported. The strategy employs a variety of amino alcohols/amines and proceeds with 6 + 4/6 + 5 and 6 + 1 cycloetherification pathways in a highly chemo- and regioselective fashion to obtain skeletally and structurally diverse, polycyclic, 10- to 11- and 7-membered benzo-fused sultams for broad-scale screening.
