185-69-3 Usage
General Description
1-Azaspiro[2.5]octane, also known as homotropane, is a bicyclic heterocyclic organic compound. It possesses a seven-membered, nitrogen-containing ring and is used in the synthesis of pharmaceuticals and agrochemicals. This chemical has been studied for its potential use as a selective norepinephrine reuptake inhibitor and has shown promise in the treatment of conditions like depression, anxiety, and attention-deficit hyperactivity disorder. Additionally, 1-Azaspiro[2.5]octane has been investigated for its potential as a chiral ligand and as a building block for the synthesis of complex organic molecules. The compound has shown to have a wide range of applications in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 185-69-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,8 and 5 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 185-69:
(5*1)+(4*8)+(3*5)+(2*6)+(1*9)=73
73 % 10 = 3
So 185-69-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H13N/c1-2-4-7(5-3-1)6-8-7/h8H,1-6H2
185-69-3Relevant articles and documents
Modular, One-Pot, Sequential Aziridine Ring Opening-SNAr Strategy to 7-, 10-, and 11-Membered Benzo-Fused Sultams
Loh, Joanna K.,Asad, Naeem,Samarakoon, Thiwanka B.,Hanson, Paul R.
, p. 9926 - 9941 (2015/11/03)
The generation of common and stereochemically rich medium-sized benzo-fused sultams via complementary pairing of heretofore-unknown (o-fluoroaryl)sulfonyl aziridine building blocks with an array of amino alcohols/amines in a modular one-pot, sequential protocol using an aziridine ring opening and intramolecular nucleophilic aromatic substitution is reported. The strategy employs a variety of amino alcohols/amines and proceeds with 6 + 4/6 + 5 and 6 + 1 cycloetherification pathways in a highly chemo- and regioselective fashion to obtain skeletally and structurally diverse, polycyclic, 10- to 11- and 7-membered benzo-fused sultams for broad-scale screening.
