1906-96-3Relevant articles and documents
-
Daviaud,G.,Miginiac,P.
, p. 997 - 1000 (1972)
-
Novel linker compound and Site-Specific compounds of Antibody-Drug Conjugate Comprising the Same
-
Paragraph 0223; 0321-0326, (2020/02/07)
The present invention relates to a novel linker compound, and relates to a site-specific antibody-drug conjugate (ADC) compound comprising the same, a method for manufacturing the same, and an anticancer composition comprising the same as an active component. The linker compound produces a uniform ADC compound with excellent site specificity in manufacturing an ADC compound, and the ADC compound comprising the same exhibits an excellent anticancer effect.COPYRIGHT KIPO 2020
A general synthetic approach to para-cyclophanes via ring-closing metathesis
Kotha, Sambasivarao,Shirbhate, Mukesh E.
, p. 1483 - 1494 (2016/02/26)
A new methodology for the synthesis para-cyclophanes and longithorone C frameworks has been demonstrated via alkylation, ceric ammonium nitrate (CAN) oxidation and ring-closing metathesis as key steps.
Intramolecular palladium-catalyzed alkene carboalkynylation
Nicolai, Stefano,Swallow, Peter,Waser, Jerome
supporting information, p. 5959 - 5964 (2015/08/03)
Abstract Carbocycles are essential building blocks for the synthesis of natural and synthetic bioactive compounds. Herein, we report the first example of palladium-catalyzed intramolecular carboalkynylation of non-activated olefins. Using activated carbon