194864-02-3Relevant articles and documents
A Mild and Convenient Semi-Synthesis of Docetaxel from 10-Deacetyl Baccatin III
Zhou, Hui,Chen, Dahai,Gao, Hongwei,Li, Qingeng
, p. 450 - 452 (2010)
A novel protocol for the semi-synthesis of docetaxel was achieved in four steps from 10-deacetyl baccatin III with an overall yield of 50%. The key step is the selective protection of the C(7) and C(10) hydroxyl groups of 10-deacetyl baccatin III, utilizi
TAXANE AND ABEO-TAXANE ANALOGS
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Paragraph 0068; 0092, (2013/07/25)
The present application discloses new taxane analogs, intermediates and methods for producing them. The present application is also directed to pharmaceutical formulations comprising abeo-taxanes and methods of treating cancer with the abeo-taxanes.
TAXANE ANALOGS FOR THE TREATMENT OF BRAIN CANCER
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Page/Page column 8-9, (2008/12/07)
Provided herein are compounds and methods for the treatment of brain cancer in a mammal, wherein the method comprises the administration to the mammal a compound that stabilizes tubulin dimers or microtubles at G2-M interface during mitosis but is not a s