197632-77-2

Basic information

• Product Name: N-Fmoc-N-Methyl-O-tert-butyl-L-serine
• Synonyms: N-Fmoc-N-Methyl-O-tert-butyl-L-serine;(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-tert-butoxypropanoic acid;N-FMoc-O-tert-butyl-N-Methyl-L-serine, 97%;Fmoc-N-Me-L-Ser(tBu)-OH;Fmoc-N-methyl-O-tert-butyl-L-serine≥ 98% (HPLC);N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-ALPHA-METHYL-O-T-BUTYL-L-SERINE;N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-ALPHA-METHYL-O-TERT-BUTYL-L-SERINE;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-ALPHA-METHYL-O-T-BUTYL-L-SERINE
• CAS NO: 197632-77-2
• Molecular Formula: C23H27NO5
• Molecular Weight: 397.46
• EINECS: 1533716-785-6
• Product Categories: Serine [Ser, S];N-Methyl Amino Acids;Fmoc-Amino acid series;amino acids
• Mol File: 197632-77-2.mol

Chemical Properties

• Melting Point: 213-218℃
• Boiling Point: 557.5 °C at 760 mmHg
• Flash Point: 291 °C
• Appearance: White to off-white/Crystalline Solid
• Density: 1.204 g/cm³
• Vapor Pressure: 2.89E-13mmHg at 25°C
• Refractive Index: 1.573
• Storage Temp.: -15°C
• PKA: 3.46±0.10(Predicted)
• CAS DataBase Reference: N-Fmoc-N-Methyl-O-tert-butyl-L-serine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Fmoc-N-Methyl-O-tert-butyl-L-serine(197632-77-2)
• EPA Substance Registry System: N-Fmoc-N-Methyl-O-tert-butyl-L-serine(197632-77-2)

Safety Data

• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 197632-77-2(Hazardous Substances Data)

Usage

Chemical Properties

White to off-white crystalline powder

InChI:InChI=1/C23H27NO5/c1-23(2,3)29-14-20(21(25)26)24(4)22(27)28-13-19-17-11-7-5-9-15(17)16-10-6-8-12-18(16)19/h5-12,19-20H,13-14H2,1-4H3,(H,25,26)/t20-/m0/s1

Upstream product

• 186581-53-3 diazomethane 
• 941296-82-8 N-nosyl-O-tert-butyl-L-serine 
• 28920-43-6 (fluorenylmethoxy)carbonyl chloride 
• 67-56-1 methanol 
• 18822-58-7 (S)-O-tert-butylserine 

Relevant articles and documents

Solid-phase synthesis of N-nosyl- and N-Fmoc-N-methyl-α-amino acids

(Chemical Equation Presented) We report here a convenient and simple solid-phase synthesis of N-nosyl-N-methyl-α-amino acids and N-Fmoc-N-methyl-α-amino acids, important building blocks for the synthesis of conformationally restricted and protease-resista

Solid phase synthesis of Fmoc N-methyl amino acids: Application of the Fukuyama amine synthesis

N-Methyl amino acids and their Fmoc derivatives are synthesized in high yield and purity on solid support using the Fukuyama amine synthesis protocol.