19924-43-7Relevant articles and documents
Preparation method of m-methoxyphenethylamine
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Paragraph 0017; 0049-0052; 0055-0058; 0061-0064, (2021/11/14)
The invention discloses a preparation method of m-methoxyethylamine, and relates to the field of organic synthesis preparation chemistry. The preparation method comprises the following steps: adding M-methoxybenzyl chloride to an aqueous solution of cyanide, carrying out cyanation reaction at 60 - 95 °C DEG C, generating M-methoxycyanide, and then cooling and crystallizing in acetone to obtain m-methoxycyanide crystals. A proper amount of ammonia gas is introduced into the solvent, then a proper amount of ammonia gas is introduced, and then hydrogen is introduced to carry out catalytic hydrogenation reaction at a temperature 110 - 160 °C, and the hydrogenated product is distilled under reduced pressure to obtain m-methoxyethylamine. The preparation method of the meta-methoxyethylamine is simple, the raw materials are easily available, the process is easy to control, the cost is low, and the method has the characteristics of high yield, high purity, environmental friendliness and the like, and is suitable for industrial production.
Crown ether functionalized magnetic hydroxyapatite as eco-friendly microvessel inorganic-organic hybrid nanocatalyst in nucleophilic substitution reactions: an approach to benzyl thiocyanate, cyanide, azide and acetate derivatives
Azaroon, Maedeh,Kiasat, Ali Reza
, (2017/10/09)
In this paper, high catalytic activity of 4′,4″-diformyl dibenzo-18-crown-6 anchored onto the functionalized magnetite hydroxyapatite (γ-Fe2O3@HAp–Crown) as a new, versatile and magnetically recoverable catalyst, was prepared. It evaluated as phase-transfer catalyst and molecular host system for nucleophilic substitution reactions of benzyl halides with thiocyanate, cyanide, azide and acetate anions in water. No evidence for the formation of by-products was observed and the products obtained in pure form without further purification. The nanocomposite was easily removed from solution via application of a magnetic field, allowing straightforward recovery and reuse. The synthesized nanocomposite was characterized by several techniques such as FT-IR, TGA-DTG, EDX, XRD, BET, FE-SEM, TEM and VSM.
Ionic liquid-induced conversion of methoxymethyl-protected alcohols into nitriles and iodides using [Hmim][NO3]
Noei, Jalil,Mirjafari, Arsalan
supporting information, p. 4424 - 4426 (2014/08/05)
This Letter reports a one-pot efficient conversion of methoxymethyl-ethers into their corresponding nitriles and iodides using the ionic liquid, 1-methyl-3H-imidazolium nitrate ([Hmim][NO3]) under microwave irradiation. A variety of products were prepared in high yields using this method.