200006-83-3Relevant articles and documents
Discovery and SAR of Org 24598 - A selective glycine uptake inhibitor
Brown, Angus,Carlyle, Ian,Clark, John,Hamilton, William,Gibson, Samuel,McGarry, George,McEachen, Sandra,Rae, Duncan,Thorn, Simon,Walker, Glenn
, p. 2007 - 2009 (2001)
The discovery of Org 24598, one of the first potent and selective inhibitors of the glycine transporter is discussed. In vitro structure-activity relationships (SARs) data for interaction of a ligand with this system is discussed.