201942-94-1

Basic information

• Product Name: (R)-2-Thiophen-2-ylthiazolidine-4-carboxylic acid
• Synonyms: (R)-2-Thiophen-2-ylthiazolidine-4-carboxylic acid;(4R)-2-(thiophen-2-yl)thiazolidine-4-carboxylic acid
• CAS NO: 201942-94-1
• Molecular Formula: C₈H₉NO₂S₂
• Molecular Weight: 215.29256
• Mol File: 201942-94-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-2-Thiophen-2-ylthiazolidine-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-Thiophen-2-ylthiazolidine-4-carboxylic acid(201942-94-1)
• EPA Substance Registry System: (R)-2-Thiophen-2-ylthiazolidine-4-carboxylic acid(201942-94-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 201942-94-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(R)-2-Thiophen-2-ylthiazolidine-4-carboxylic acid is used as a key compound in the development of drugs for treating medical conditions such as diabetes and cardiovascular diseases. Its molecular structure allows for potential interactions with biological targets, making it a valuable asset in drug discovery and medicinal chemistry research.
Used in Organic Synthesis:
(R)-2-Thiophen-2-ylthiazolidine-4-carboxylic acid is also utilized as a building block or intermediate in organic synthesis, contributing to the creation of more complex molecules with specific applications in various industries.
Used in Chemical Processes:
(R)-2-Thiophen-2-ylthiazolidine-4-carboxylic acid may have additional applications in chemical processes, where its unique properties can be harnessed to improve reaction efficiency, yield, or selectivity, further expanding its value in the field of chemistry.

Upstream product

• 98-03-3 thiophene-2-carbaldehyde 
• 52-90-4 L-Cysteine 

Downstream Products

• 72678-60-5 (4R)-3-[(2S)-S-Benzoyl-3-mercapto-2-methylpropanoyl]-2-(2-thienyl)-4-thiazolidinecarboxylic acid 
• 72678-58-1 (R)-3-(3-Benzoylsulfanyl-propionyl)-2-thiophen-2-yl-thiazolidine-4-carboxylic acid 

Relevant articles and documents

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A series of 2-arylthiazolidine-4-carboxylic acid amide derivatives were synthesized and their cytotoxic activity against three cancer cell lines (PC-3, SKOV3 and MDA-MB231) was evaluated. Various structural modifications were tried including modifications

Azafulvenium methides: New extended dipolar systems

The transient 1-azafulvenium methides 24, 26 and 28 generated by thermal extrusion of sulfur dioxide from pyrrolo[1,2-c][1,3]thiazole 2,2-dioxide 20 (R = Me), 22 and 23 undergo sigmatropic [1,8]H shifts and the 1-acyl derivatives 30 electrocyclise to give novel pyrrolo[1,2-c][1,3]oxazines 32. The analogous 1,2-diazafulvenium methide 36 has been intercepted in [8π + 2π] cycloadditions with electron-rich silylated acetylenes to give adducts 37-40. This behaviour is partially explained by Frontier MO theory.