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BOC-D-GLN(TRT)-OH is a chemical compound that serves as an essential building block in peptide synthesis. It is a derivative of the amino acid glutamine, featuring a t-butoxycarbonyl (BOC) protecting group on the N-terminal amine and a trityl (TRT) protecting group on the side chain amine. These protecting groups ensure the stability and ease of handling of BOC-D-GLN(TRT)-OH, making it a valuable reagent for the production of peptides in various applications.

210750-95-1

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  • D-Glutamine,N2-[(1,1-dimethylethoxy)carbonyl]-N-(triphenylmethyl)-

    Cas No: 210750-95-1

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210750-95-1 Usage

Uses

Used in Peptide Synthesis:
BOC-D-GLN(TRT)-OH is used as a building block for the construction of customized peptides in laboratory settings. Its protecting groups facilitate the controlled addition of amino acids during peptide synthesis, allowing for the creation of peptides with specific sequences and functions.
Used in Research Applications:
BOC-D-GLN(TRT)-OH is used as a reagent in research settings to study the structure, function, and interactions of peptides. Its stable and easily handled nature makes it suitable for various experimental techniques, such as mass spectrometry, nuclear magnetic resonance (NMR), and X-ray crystallography.
Used in Pharmaceutical Applications:
BOC-D-GLN(TRT)-OH is used in the development of therapeutic peptides for the treatment of various diseases and conditions. Its role in peptide synthesis enables the production of peptides with specific biological activities, such as antimicrobial, antiviral, or anticancer properties.
Used in Industrial Applications:
BOC-D-GLN(TRT)-OH is employed in the production of peptides for various industrial applications, such as food additives, cosmetic ingredients, and agricultural products. Its versatility in peptide synthesis allows for the creation of peptides with specific properties, such as taste enhancement, skin protection, or plant growth regulation.

Check Digit Verification of cas no

The CAS Registry Mumber 210750-95-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,0,7,5 and 0 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 210750-95:
(8*2)+(7*1)+(6*0)+(5*7)+(4*5)+(3*0)+(2*9)+(1*5)=101
101 % 10 = 1
So 210750-95-1 is a valid CAS Registry Number.

210750-95-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name BOC-D-GLN(TRT)-OH

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:210750-95-1 SDS

210750-95-1Relevant articles and documents

Protected amino acids and process for the preparation thereof

-

, (2008/06/13)

Compounds of the formula I, STR1 in which 'R1 is an amino protective group, and n stands for 1 or 2, R1 denotes hydrogen or an amino protective group, R2 denotes hydrogen or a carboxyl protective group and R3 denotes triphenylmethyl, 4-monomethoxy-trityl or 4,4'-dimethoxy-trityl, and reactive carboxylic acid derivatives of such compounds of the formula I in which R2 stands for hydrogen, are described. These compounds can be used as starting materials for the preparation of peptides. They are more suitable for this than are analogous compounds of the formula I in which R3 denotes hydrogen or one of the carbamoyl protective groups hitherto customary.

Protection of carboxamide functions by the trityl residue. Application to peptide synthesis

Sieber,Riniker

, p. 739 - 742 (2007/10/02)

Carboxamide functions may be tritylated by an acid-catalyzed reaction with triphenylmethanol and acetic anhydride in glacial acetic acid. The ω-trityl group of asparagine and glutamine is cleavable by TFA, but stable to strong mineral acids in aqueous solution, as well as to nucleophiles and bases. In peptide syntheses, it is ideally suited for combination with side-chain protections of the t.butyl-type.

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