2217-14-3Relevant articles and documents
Enantioselective distribution of amino-alcohols in a liquid-liquid two-phase system containing dialkyl L-tartrate and boric acid
Abe,Shoji,Kobayashi,Qing,Asai,Nishizawa
, p. 262 - 265 (2007/10/02)
Racemic amino-alcohols such as pindolol, propranolol, alprenolol and bucumolol enantiomers exhibited different distribution behaviors in a two-phase system consisting of a chloroform solution of didodecyl L-tartrate and an aqueous solution of boric acid. It seemed that a borate complex of the 1,2-diol group of the tartrate and the amino-alcohol was formed in the system. In the case of pindolol, one enantiomer was preferentially extracted into the organic phase (x 2.20) at equilibrium.