2217-56-3

Basic information

• Product Name: Benzene,1,1'-oxybis[2,4-dinitro- (9CI)
• Synonyms: Ether,bis(2,4-dinitrophenyl) (6CI,7CI,8CI); 2,2',4,4'-Tetranitrodiphenyl ether;2,2',4,4'-Tetranitrodiphenyl oxide; Bis(2,4-dinitrophenyl) ether;Di(2,4-dinitrophenyl) ether; NSC 20809
• CAS NO: 2217-56-3
• Molecular Formula: C12H6 N4 O9
• Molecular Weight: 350.201
• Mol File: 2217-56-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 460.4°Cat760mmHg
• Flash Point: 200.9°C
• Density: 1.688g/cm³
• CAS DataBase Reference: Benzene,1,1'-oxybis[2,4-dinitro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene,1,1'-oxybis[2,4-dinitro- (9CI)(2217-56-3)
• EPA Substance Registry System: Benzene,1,1'-oxybis[2,4-dinitro- (9CI)(2217-56-3)

Safety Data

• Hazardous Substances Data: 2217-56-3(Hazardous Substances Data)

Upstream product

• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 51-28-5 2,4-Dinitrophenol 
• 610-31-1 1,2,4-trinitrobenzene 
• 101-84-8 diphenylether 
• 7697-37-2 nitric acid 
• 70-34-8 2,4-Dinitrofluorobenzene 
• 56966-61-1 5-bromo-2--phenoxynitrobenzene 
• 620-88-2 4-nitrophenyl phenyl ether 
• 2486-07-9 2,4-dinitrophenyl phenyl ether 
• 2363-36-2 (2,4-dinitro-phenyl)-(4-nitro-phenyl)-ether 
• 7497-12-3 bis(2,4-dinitrophenyl) carbonate 
• 101-63-3 bis(4-nitrophenyl)ether 
• 21969-04-0 1-(4-nitrophenoxy)-4-bromobenzene 

Downstream Products

• 28124-29-0 phenazine-1,7-diamine 
• 113797-77-6 bis-(2,4-diamino-phenyl)-ether 
• 51-28-5 2,4-Dinitrophenol 
• 97-02-9 2,4-Dinitroanilin 
• 961-68-2 N-phenyl-2,4-dinitroaniline 
• 63441-08-7 bis(2,4,6-trinitrophenyl) ether 
• 120209-97-4 2,7-Diaminophenazine 
• 98221-60-4 1-(2,4-dinitro-phenyl)-pyridinium; 2,4-dinitro-phenolate 

Relevant articles and documents

Clean production process for producing nitrobenzene alkoxy ether by using nitrohalogenated benzene

The invention provides a clean production process for producing nitrobenzene alkoxy ether by using nitrohalogenated benzene. The specific production steps comprise: proportionally adding one or more than one non-polar solvents into a reactor, adding molten nitrohalogenated benzene into the reactor, uniformly stirring, and adding alkali metal alkoxide into the reactor at a constant speed; after thereaction is finished, adding water to washing the inorganic matters generated in the reaction process while recovering the solvent. According to the invention, the production process is simple, the catalyst separation efficiency in the reaction process is high, other substances irrelevant to the reaction are not added in the reaction process, the purity is high, the yield is high, byproducts arelow, the wastewater amount is low, and the reaction period is short; and the reaction device is operated in a totally-enclosed manner, so that the operation environment is improved, the harm to humanhealth is reduced, and the cost is saved.

Metal- and Phenol-Free Synthesis of Biaryl Ethers: Access to Dibenzobistriazolo-1,4,7-oxadiazonines and Vancomycin-Like Glyco-Macrocycles as Antibacterial Agents

An efficient synthesis of biaryl ethers, from electron-deficient aryl halides using NaH/DMSO under metal- and phenol-free conditions, has been achieved to access dibenzo-bistriazolo-1,4,7-oxadiazonines and vancomycin-like glyco-macrocycles. A 44-membered glyco-macrocycle showed promising activity against vancomycin-resistant Staphylococcus aureus (VRSA).

Method for the preparation of diphenyl ether compounds

The invention relates to a method for preparing a diphenyl ether compound. The method is characterized by comprising the following technical steps of: (1) adding a halogenated benzene derivative and a bis(pinacolato)diboron into a reaction vessel, adding copper chloride or aluminum chloride and 1,2-bi(diphenylphosphine) ethane as a catalyst, then adding alkaline and an organic solvent, and reacting at 25-160 DEG C for 6-24 hours; and (2) after extracting a reaction solution obtained from the step (1) by using ethyl acetate, purifying by a 200-300 meshes silica gel column, pre-eluting the silica gel column by using 20-50 mL of normal hexane, eluting by adopting an eluent at a flow speed of 1-2 mL/min for 3-6 hours, and removing the solvent to obtain the diphenyl ether compound. The method for preparing the diphenyl ether compound, disclosed by the invention, no only overcomes the disadvantage of the use of phenolic substances in a reaction process, but also has the advantages of mild reaction condition and high yield.