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21969-04-0

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21969-04-0 Usage

General Description

1-bromo-4-(4-nitrophenoxy)benzene is a chemical compound with the molecular formula C12H8BrNO3. It is a benzene derivative with a bromine atom and a 4-nitrophenoxy group attached to the 1 and 4 positions, respectively. 1-bromo-4-(4-nitrophenoxy)benzene is commonly used in organic synthesis and pharmaceutical research as a reagent and intermediate. It is also utilized in the production of agrochemicals and dyes. 1-bromo-4-(4-nitrophenoxy)benzene is a white to beige crystalline solid with a melting point of around 85-87°C and is sparingly soluble in water but soluble in organic solvents. It should be handled and stored with caution as it is toxic if ingested or inhaled and may cause skin and eye irritation.

Check Digit Verification of cas no

The CAS Registry Mumber 21969-04-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,9,6 and 9 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 21969-04:
(7*2)+(6*1)+(5*9)+(4*6)+(3*9)+(2*0)+(1*4)=120
120 % 10 = 0
So 21969-04-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H8BrNO3/c13-9-1-5-11(6-2-9)17-12-7-3-10(4-8-12)14(15)16/h1-8H

21969-04-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-bromophenoxy)-4-nitrobenzene

1.2 Other means of identification

Product number -
Other names (4-bromo-phenyl)-(4-nitro-phenyl)-ether

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:21969-04-0 SDS

21969-04-0Relevant articles and documents

Cu(I)-PNF, an organic-based nanocatalyst, catalyzed C-O and C-S cross-coupling reactions

Taherinia, Zahra,Ghorbani-Choghamarani, Arash

, p. 46 - 52 (2019/01/10)

Peptide nanofiber has been prepared via a self-assembly protocol and decorated with Cu(I) to prepare a nanostructural catalyst. The catalytic activity of this prepared nanomaterial (Cu(I)-PNF) was examined in C-O and C-S cross-coupling reactions. Compared with conventional copper-ligand catalytic systems, CuNP-PNF has unique advantages such as water solubility, high efficiency, and low cost, which makes it a highly efficient and beneficial catalyst to reuse in cross-coupling reactions.

Synthesis, SAR and molecular docking study of novel non-β-lactam inhibitors of TEM type β-lactamase

Antipin, Roman L.,Beshnova, Daria A.,Petrov, Rostislav A.,Shiryaeva, Anna S.,Andreeva, Irina P.,Grigorenko, Vitaly G.,Rubtsova, Maya Yu.,Majouga, Alexander G.,Lamzin, Victor S.,Egorov, Alexey M.

supporting information, p. 1588 - 1592 (2017/03/17)

The novel classes of acylated phenoxyanilide and thiourea compounds were investigated for their ability to inhibit TEM type β-lactamase enzyme. Two compounds 4g and 5c reveal the inhibition potency in micromolar range and show their action by non-covalent binding in the vicinity of the TEM-171 active site. The structure activity relationship around carbon chain length and different substituents in ortho- and para-positions of acylated phenoxyanilide as well as molecular modelling study has been performed.

Synthesis and biological evaluation of pentanedioic acid derivatives as farnesyltransferase inhibitors

Yang, Liuqing,Liu, Wei,Mei, Hanbing,Zhang, Yuan,Yu, Xiaojuan,Xu, Yufang,Li, Honglin,Huang, Jin,Zhao, Zhenjiang

supporting information, p. 671 - 676 (2015/04/27)

Structure-based virtual screening of a commercial library identified pentanedioic acid derivatives (6 and 13b) as a kind of novel scaffold farnesyltransferase inhibitors (FTIs). Chemical modifications of the lead compounds, biological assays and analysis of the structure-activity relationships (SAR) were conducted to discover more potent FTIs. Some of them displayed excellent inhibition against FTase, and among them, the most active compound 13n with an IC50 value of 0.0029 μM and SAR analysis might be helpful to the discovery of more potent FTIs. This journal is

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