22604-07-5 Usage
Description
1-Naphthalenol,6-methoxy-, commonly known as Thymol blue, is a pH indicator that appears as a brownish-green or brownish-blue crystalline powder. It is a chemical often utilized in laboratories and scientific research, with a color change range from red at pH 1.2 to 2.8 and blue at pH 8.0 to 9.6. Thymol blue is soluble in ethanol and ether, slightly soluble in water, but insoluble in benzene and petroleum ether. Although it is considered harmless in small amounts, it can cause harm if ingested or if it comes in contact with the skin in large quantities. According to the Globally Harmonized System (GHS) of Classification and Labeling of Chemicals, it is classified as a substance that causes severe eye damage.
Uses
Used in Laboratory Applications:
1-Naphthalenol,6-methoxyis used as a pH indicator for monitoring the acidity or alkalinity of solutions in laboratory settings. Its color change properties make it a valuable tool for scientific research and experiments.
Used in Scientific Research:
1-Naphthalenol,6-methoxyis used as a pH indicator in various scientific research projects, allowing researchers to accurately measure and analyze the pH levels of different substances and solutions. This is crucial for understanding chemical reactions and processes that are dependent on pH conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 22604-07-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,6,0 and 4 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 22604-07:
(7*2)+(6*2)+(5*6)+(4*0)+(3*4)+(2*0)+(1*7)=75
75 % 10 = 5
So 22604-07-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H10O2/c1-13-9-5-6-10-8(7-9)3-2-4-11(10)12/h2-7,12H,1H3
22604-07-5Relevant articles and documents
Synthesis of substituted (S)-2-aminotetralins via ring-opening of aziridines prepared from l-aspartic acid β-tert-butyl ester
Aaseng, Jon Erik,Gautun, Odd R.
scheme or table, p. 8982 - 8991 (2011/01/04)
This paper describes the total synthesis of the hydrochloride salts of (2S)-2-amino-7-methoxytetralin (21-HCl) and (2S)-2-amino-6-fluoro-7- methoxytetralin (ST1214), from a common enantiomerically pure aziridine 4b, which was available from l-aspartic acid β-tert-butyl ester. The synthesis of 21-HCl and ST1214 proceeded in nine steps and 5 and 6% overall yields, respectively. Key steps are the regioselective ring-opening of 4b with ArMgBr/CuBr·SMe2 and the intramolecular Friedel-Crafts cyclisation providing α-tetralone. Substituted naphthalenes were formed as side products in the latter reaction.
N-1H-tetrazol-5-yl-2-naphthalene carboxamides and their use as antiallergy and antiinflammatory agents
-
, (2008/06/13)
Novel naphthalene derivatives having antiallergy and antiinflammatory activity.