23235-61-2Relevant articles and documents
Urea as an efficient reagent for the synthesis of 3-ethyl-3-(hydroxymethyl)oxetane: A novel component in cationic ring-opening polymerisation
Annby, Ulf,Rehnberg, Nicola,Samuelsson, Jesper,Teichert, Oliver
, p. 568 - 571 (2001)
Urea is a very attractive chemical raw material for large-scale production as it combines low cost with virtually unlimited supply and essentially no toxic effects. Here, we present a study on its use in the dehydration of trimethylolpropane with formation of 3-ethyl-3-(hydroxymethyl)oxetane. The reaction consists of carbonylation of trimethylolpropane and subsequent extrusion of carbon dioxide. The first step was run at a temperature of 120-160 °C at a pressure of approximately 300 mmHg for 1-5 h. Most likely, carbamates of TMP constitute the major product. In the latter step, the temperature was increased to 195-215 °C, the pressure was reduced to 10-50 mmHg, and the final product was isolated by distillation. A spiroorthocarbonate of TMP was formed as an unexpected by-product. The process has been demonstrated on a multikilogram scale. Toxicological screening revealed 3-ethyl-3-(hydroxymethyl)oxetane to be irritating to eye but not to skin.
A method of manufacturing a polyhydric alcohol ether
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Paragraph 0068; 0077, (2017/01/26)
[Problem] The purpose of the invention is to react pentaerythritol, trimethylolpropane, or another such polyhydric alcohol with a carbonic acid ester to obtain dipentaerythritol, ditrimethylolpropane, or another such polyhydric alcohol ether at a good yield. [Solution] A method for producing a polyhydric alcohol ether characterized by the joint use of the following catalyst A and catalyst B when reacting a polyhydric alcohol and a carbonic acid ester and producing a polyhydric alcohol ether of a structure in which the polyhydric alcohol is dehydrated and condensed between molecules. Catalyst A: one or more compounds selected from the group consisting of compounds containing an alkali metal, compounds containing an alkaline earth metal, amines or salts thereof or complexes thereof, and semicarbazides or salts thereof. Catalyst B: one or more compounds selected from the group consisting of compounds containing boron, compounds containing titanium, and compounds containing zirconium.
PROCESS FOR PRODUCTION OF DITRIMETHYLOLPROPANE
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Paragraph 0088-0089, (2014/05/20)
Provided is a method for producing di-TMP by reacting n-butyl aldehyde (NBD), formaldehyde and a base, said method including a first step of reacting the NBD, formaldehyde (1) and a base (I) to obtain a reaction mixture solution containing trimethylolpropane (TMP), di-TMP and 2-ethyl-2-propenal (ECR); a second step of distilling the reaction mixture solution to recover the ECR therefrom; and a third step of sequentially adding the ECR recovered by distillation, and adding at least one of a base (II) and formaldehyde (2), to the reaction mixture solution from which the ECR has been recovered by distillation, and thereby allowing a reaction for production of the di-TMP to proceed gradually, in which TMP is added in any one of the first to third steps or in plural steps of the first to third steps.
