247259-33-2Relevant articles and documents
TETRAHYDROIMDIDAZOPYRAZINE DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS
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, (2014/05/07)
The disclosure generally relates to the novel compounds of formula I, including pharmaceutically acceptable salts, which are CGRP receptor antagonists. The disclosure also relates to pharmaceutical compositions and methods for using the compounds in the t
Novel therapeutic agents for the treatment of migraine
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Page/Page column 47, (2010/02/14)
The present invention relates to compounds of Formula (I) as antagonists of calcitonin gene-related peptide receptors (“CGRP-receptor”), pharmaceutical compositions comprising them, methods for identifying them, methods of treatment using them and their u
Synthesis and Pharmacology of Site-Specific Cocaine Abuse Treatment Agents: The Role of the Phenyl Group in Highly Modified Methylphenidate analogs as Dopamine Uptake Inhibitors
Deutsch, Howard M.,Dunn, Travis,Ye, Xiaocong,Schweri, Margaret M.
, p. 213 - 222 (2007/10/03)
A series of modified methylphenidate derivatives was synthesized and tested for inhibitory potency in [3H]WIN 35,428 binding and [3H]dopamine uptake assays using rat striatal tissue. In these compounds the role of the phenyl ring was investigated by its r