81270-37-3

Basic information

• Product Name: PIPERIDIN-4-YL-ACETIC ACID METHYL ESTER HYDROCHLORIDE
• Synonyms: PIPERIDIN-4-YL-ACETIC ACID METHYL ESTER HYDROCHLORIDE ;(4-Piperidyl)acetic Acid Methyl Ester Hydrochloride;Methyl (4-Piperidyl)acetate Hydrochloride;Methyl piperidin-4-ylacetate hydrochloride;4-(2-Methoxy-2-oxoethyl)piperidine hydrochloride;PIPERIDIN-4-YL-ACETIC ACID METHYL ESTER HCL;Ethyl 2-piperidin-4-ylacetateHcl;4-(2-Methoxy-2-oxoethyl)piperidine hydrochloride, (Piperidin-4-yl)acetic acid methyl ester hydrochloride
• CAS NO: 81270-37-3
• Molecular Formula: C8H16ClNO2
• Molecular Weight: 193.67114
• Mol File: 81270-37-3.mol
• Article Data: 4

Chemical Properties

• Melting Point: 155 °C
• Boiling Point: 253 °C at 760 mmHg
• Flash Point: 106.8 °C
• Appearance: /
• Vapor Pressure: 0.0148mmHg at 25°C
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Water Solubility: Soluble in water
• CAS DataBase Reference: PIPERIDIN-4-YL-ACETIC ACID METHYL ESTER HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: PIPERIDIN-4-YL-ACETIC ACID METHYL ESTER HYDROCHLORIDE(81270-37-3)
• EPA Substance Registry System: PIPERIDIN-4-YL-ACETIC ACID METHYL ESTER HYDROCHLORIDE(81270-37-3)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 81270-37-3(Hazardous Substances Data)

Usage

Chemical Properties

White powder

InChI:InChI=1/C8H15NO2.ClH/c1-11-8(10)6-7-2-4-9-5-3-7;/h7,9H,2-6H2,1H3;1H

Upstream product

• 175213-46-4 1-t-Butoxycarbonyl-4-(methoxycarbonylmethyl)piperidine 
• 157688-46-5 2-(1-(tert-butoxycarbonyl)piperidin-4-yl)acetic acid 
• 54401-85-3 pyridin-4-yl-acetic acid ethyl ester 
• 70199-68-7 methyl 4-pyridylacetate hydrochloride 

Downstream Products

• 960391-50-8 C₂₆H₃₅F₂N₃O₃ 
• 1252900-72-3 benzyl 4-[4-(2-methoxy-2-oxoethyl)piperidin-1-yl]benzoate 

Relevant articles and documents

BENZIMIDAZOLE DERIVATIVES AS MODULATORS OF ROR-GAMMA

Provided are novel compounds of Formula I: pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by RORy. Also provided are pharmaceutical compositions comprising the novel compounds of Formula I and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

BENZIMIDAZOLE DERIVATIVES WHICH ARE TO BE USED AS ANTAGONIST FOR THE CB1-RECEPTOR

Compounds of formula I or pharmaceutically acceptable salts thereof: wherein X, A, R1, R2, R3 and R4 are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.