252010-70-1

Basic information

• Product Name: Pyrazino[2,3-b]pyrazine, decahydro-4a,8a-dimethyl-, cis- (9CI)
• Synonyms: Pyrazino[2,3-b]pyrazine, decahydro-4a,8a-dimethyl-, cis- (9CI);CIS-4A,8A-DIMETHYLDECAHYDROPYRAZINO[2,3-B]PYRAZINE
• CAS NO: 252010-70-1
• Molecular Formula: C8H18N4
• Molecular Weight: 170.25532
• Product Categories: PIPERIDINE
• Mol File: 252010-70-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pyrazino[2,3-b]pyrazine, decahydro-4a,8a-dimethyl-, cis- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrazino[2,3-b]pyrazine, decahydro-4a,8a-dimethyl-, cis- (9CI)(252010-70-1)
• EPA Substance Registry System: Pyrazino[2,3-b]pyrazine, decahydro-4a,8a-dimethyl-, cis- (9CI)(252010-70-1)

Safety Data

• Hazardous Substances Data: 252010-70-1(Hazardous Substances Data)

Upstream product

• 6780-13-8 1,2-ethanediamine monohydrate 
• 431-03-8 dimethylglyoxal 
• 15986-92-2 5,6-dimethyl-2,3-dihydropyrazine 
• 107-15-3 ethylenediamine 
• 1121-22-8 trans-1,2-Diaminocyclohexane 

Relevant articles and documents

A diamine-exchange reaction of dihydropyrazines

Dihydropyrazines reacted with 1,2-diamines to form tetraazadecalins as intermediates, and then the reaction proceeded forward to dissociate into alternate dihydropyrazine and diamine, or backward to dissociate into the starting materials in certain equilibrium. The product distribution is controlled by diamine-exchange equilibrium reaction. The various equilibrium reactions were analyzed by NMR spectroscopy.

Products from a novel reaction of dihydropyrazines with vichinaldiamines

Dihydropyrazines such as 2,3-dihydro-5,6-dimethylpyrazine reacted with 1,2-diamines like ethylenediamine to form cis-tetraazadecalins (TADs) as crystalline products. The NMR spectra of the products in CDCl3 or CD3CN at -20 ~ -60°C exhibited the signals due to TAD. However, the NMR spectra at room temperature showed that the TAD had dissociated into its parent materials. Seven TADs were obtained by only a mixing operation at a low temperature.