2567-51-3

Basic information

• Product Name: N,N-Dibenzyl-2-chloro-acetamide
• Synonyms: N,N-Dibenzyl-2-chloro-acetamide
• CAS NO: 2567-51-3
• Molecular Formula: C₁₆H₁₆ClNO
• Molecular Weight: 273.76
• Mol File: 2567-51-3.mol

Chemical Properties

• Boiling Point: 432.1 °C at 760 mmHg
• Flash Point: 215.1 °C
• Appearance: /
• Density: 1.181 g/cm³
• Vapor Pressure: 1.14E-07mmHg at 25°C
• Refractive Index: 1.589
• CAS DataBase Reference: N,N-Dibenzyl-2-chloro-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-Dibenzyl-2-chloro-acetamide(2567-51-3)
• EPA Substance Registry System: N,N-Dibenzyl-2-chloro-acetamide(2567-51-3)

Safety Data

• Hazardous Substances Data: 2567-51-3(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
N,N-Dibenzyl-2-chloro-acetamide is used as a reactant for the diastereoand chemoselective preparation of vinyl silanes and silyl-substituted alpha, beta-unsaturated amides. This application takes advantage of the compound's reactivity and selectivity in Pd-catalyzed olefination reactions, which are crucial for the synthesis of complex organic molecules with specific stereochemistry and functional groups.
In the field of organic chemistry, N,N-Dibenzyl-2-chloro-acetamide serves as a versatile building block for the creation of a wide range of compounds with potential applications in various industries, such as pharmaceuticals, materials science, and agrochemicals. Its use in diastereoand chemoselective reactions allows for the precise control of molecular structure, which is essential for the development of effective and targeted drugs, as well as advanced materials with specific properties.
Furthermore, the compound's utility in Pd-catalyzed olefination reactions highlights its importance in modern synthetic chemistry, as this method is widely employed for the formation of carbon-carbon double bonds, a fundamental structural element in many organic molecules. The ability of N,N-Dibenzyl-2-chloro-acetamide to participate in these reactions with high selectivity makes it a valuable tool for chemists working on the design and synthesis of complex molecular architectures.

InChI:InChI=1/C16H16ClNO/c17-11-16(19)18(12-14-7-3-1-4-8-14)13-15-9-5-2-6-10-15/h1-10H,11-13H2

Upstream product

• 79-04-9 chloroacetyl chloride 
• 103-49-1 dibenzylamine 
• 4015-58-1 monochloroacetic acid anhydride 
• 22118-09-8 2-bromoacetyl chloride 

Downstream Products

• 63238-08-4 4-amino-2-methylsulfanyl-thiazole-5-carboxylic acid dibenzylamide 
• 63238-09-5 4-amino-2-ethylsulfanyl-thiazole-5-carboxylic acid dibenzylamide 
• 63238-10-8 4-Amino-N,N-dibenzyl-2-benzylthio-5-thiazolcarboxamid 
• 55097-24-0 N,N-Dibenzyl-5-amino-3-thiapentanoic Acid Amide 
• 10479-30-8 N,N-dibenzylacetamide 
• 165062-70-4 N,N-dibenzyl-α-(methoxycarbonyl)acetamide 
• 752994-27-7 2,2'-[5,6-(1,10-phenanthroline)bis(oxy)]-bis(N,N-dibenzylacetamide) 
• 489431-27-8 N,N-bis(phenylmethyl)-2-(diphenylphosphono)acetamide 
• 663936-05-8 3-amino-4-methoxymethyl-6-methyl-thieno[2,3-b]pyridine-2-carboxylic acid dibenzylamide 
• 875801-19-7 3-azido-4-methoxymethyl-6-methyl-thieno[2,3-b]pyridine-2-carboxylic acid dibenzylamide 
• 51-50-3 N,N-dibenzyl-2-chloroethanamine 
• 617695-07-5 N,N-dibenzyl-3-methylbenzofuran-2-carboxamide 
• 1428962-06-4 N,N-dibenzyl-2-((2-hydroxy-3-(1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)propyl)(methyl)amino)acetamide 
• 1428962-44-0 N,N-dibenzyl-2-((2-hydroxy-3-(1-methyl-2,4-dioxo-1,2-dihydroquinazolin-3(4H)-yl)propyl)(methyl)amino)acetamide hydrochloride 

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