286371-71-9

Basic information

• Product Name: 4-[(6,7-diMethoxy-4-quinazolinyl)oxy]aniline
• Synonyms: 4-[(6,7-diMethoxy-4-quinazolinyl)oxy]aniline
• CAS NO: 286371-71-9
• Molecular Formula: C₁₆H₁₅N₃O₃
• Molecular Weight: 297.3086
• Mol File: 286371-71-9.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-[(6,7-diMethoxy-4-quinazolinyl)oxy]aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[(6,7-diMethoxy-4-quinazolinyl)oxy]aniline(286371-71-9)
• EPA Substance Registry System: 4-[(6,7-diMethoxy-4-quinazolinyl)oxy]aniline(286371-71-9)

Safety Data

• Hazardous Substances Data: 286371-71-9(Hazardous Substances Data)

Upstream product

• 123-30-8 4-amino-phenol 
• 13790-39-1 6,7-dimethoxy-4-chloroquinazoline 
• 5653-40-7 2-Amino-4,5-dimethoxybenzoic acid 
• 26759-46-6 methyl 2-amino-4,5-dimethoxybenzoate 
• 100-02-7 4-nitro-phenol 
• 35654-56-9 6,7-dimethoxy-4-chloroquinoline 
• 13794-72-4 3H-6,7-dimethoxyquinazolin-4-one 

Relevant articles and documents

Quinazoline compound and application thereof

The invention relates to a quinazoline-containing compound as shown in a general formula (I), and a pharmaceutically acceptable salt, a solvate and a prodrug thereof, wherein substituent groups R1, R2, R3, R4, R5, R6, p, m and n are defined in the specification. The invention also relates to application of the compound shown in the general formula (I) in preparation of antitumor drugs, and also relates to application of the compound, the pharmaceutically acceptable salt, the solvate and the prodrug thereof in preparation and/or prevention and alleviation of cancers caused by tumor cells of human tissues or organs, wherein the cancers are preferably colon cancer, liver cancer, lymphoma, lung cancer, esophageal cancer, breast cancer, central nervous system tumor, melanoma, skin cancer, ovarian cancer, cervical cancer, kidney cancer, leukemia, prostate cancer, pancreatic cancer, bladder cancer, rectal cancer, osteosarcoma, nasopharyngeal cancer or gastric cancer and the like.

Multi-target kinase inhibitor, pharmaceutical composition and preparation method and application of multi-target kinase inhibitor

The invention belongs to the technical field of biological medicines, in particular relates to a multi-target kinase inhibitor and a pharmaceutical composition containing the multi-target kinase inhibitor, and also relates to a preparation method and appl

Discovery of N-(4-{[5-Fluoro-7-(2-methoxyethoxy)quinazolin-4-yl]amino}phenyl)-2-[4-(propan-2-yl)-1 H-1,2,3-triazol-1-yl]acetamide (AZD3229), a Potent Pan-KIT Mutant Inhibitor for the Treatment of Gastrointestinal Stromal Tumors

While the treatment of gastrointestinal stromal tumors (GISTs) has been revolutionized by the application of targeted tyrosine kinase inhibitors capable of inhibiting KIT-driven proliferation, diverse mutations to this kinase drive resistance to establish