32969-26-9 Usage
Description
3-Bromo-5-chlorobenzo[b]thiophene, with the molecular formula C8H4BrClS, is a heterocyclic aromatic compound that features a thiophene ring with a bromine atom at the 3-position and a chlorine atom at the 5-position. This unique structure endows it with specific reactivity and properties, making it a valuable building block in organic synthesis and pharmaceutical research.
Uses
Used in Pharmaceutical Research:
3-Bromo-5-chlorobenzo[b]thiophene is utilized as a key intermediate in the development of new drugs and materials. Its distinctive structure allows for the creation of complex molecules and biologically active compounds, which can be further explored for their therapeutic potential.
Used in Organic Synthesis:
In the field of organic synthesis, 3-Bromo-5-chlorobenzo[b]thiophene serves as a versatile precursor for the synthesis of a variety of specialty chemicals. Its reactivity and the presence of both bromine and chlorine atoms make it an attractive candidate for the formation of diverse chemical entities.
Used in Agrochemical Production:
3-Bromo-5-chlorobenzo[b]thiophene is also employed as a precursor in the production of agrochemicals. Its role in this industry is to contribute to the development of new pesticides or other agricultural products that can improve crop protection and yield.
Used in Chemical Industry:
As an important intermediate in the chemical industry, 3-Bromo-5-chlorobenzo[b]thiophene is leveraged for its wide range of potential applications. Its availability and versatility make it a crucial component in the synthesis of various compounds used across different sectors.
Check Digit Verification of cas no
The CAS Registry Mumber 32969-26-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,9,6 and 9 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 32969-26:
(7*3)+(6*2)+(5*9)+(4*6)+(3*9)+(2*2)+(1*6)=139
139 % 10 = 9
So 32969-26-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H4BrClS/c9-7-4-11-8-2-1-5(10)3-6(7)8/h1-4H
32969-26-9Relevant articles and documents
Catalytic Asymmetric Dearomative 1,3-Dipolar Cycloaddition of 2-Nitrobenzothiophenes and Isatin-Derived Azomethine Ylides
Zhao, Jian-Qiang,Zhou, Shun,Yang, Lei,Du, Hong-Yan,You, Yong,Wang, Zhen-Hua,Zhou, Ming-Qiang,Yuan, Wei-Cheng
supporting information, p. 8600 - 8605 (2021/11/13)
An enantioselective dearomative 1,3-dipolar cycloaddition of 2-nitrobenzothiophenes and isatin-derived azomethine ylides with a bifunctional hydrogen-bonding thiourea catalyst was established, giving polyheterocyclic compounds in excellent results (up to 99% yield, >20:1 dr for all cases and up to 99% ee). The enantioselectivity could be reversed by the bifunctional hydrogen-bonding squaramide catalyst containing the same chiral source as in the thiourea catalyst. DFT calculations revealed the origin of the observed stereochemistry and the reversal of enantioselectivity.
BENZOTHIOPHENE INHIBITORS OF RHO KINASE
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Page/Page column 17; 27, (2008/06/13)
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Azabicyclic inhibitors of serotonin reuptake
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, (2008/06/13)
This invention provides 3-(bicyclic heteroaryl)-8-azabicyclo[3.2.1]oct-2-enes and 3-(bicyclic heteroaryl)-8-azabicyclo[3.2.1]octanes of furmula (I) which are useful for the inhibition of serotonin reuptake in mammals. whereA-B is -C=CH- or -CH-CH2/s
