50548-46-4

Basic information

• Product Name: 1-chloro-4-(2,2-diethoxyethylsulfanyl)benzene
• CAS NO: 50548-46-4
• Molecular Formula: C₁₂H₁₇ClO₂S
• Molecular Weight: 260.7802
• Mol File: 50548-46-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 329.947°C at 760 mmHg
• Flash Point: 153.346°C
• Density: 1.149g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.537
• CAS DataBase Reference: 1-chloro-4-(2,2-diethoxyethylsulfanyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-4-(2,2-diethoxyethylsulfanyl)benzene(50548-46-4)
• EPA Substance Registry System: 1-chloro-4-(2,2-diethoxyethylsulfanyl)benzene(50548-46-4)

Safety Data

• Hazardous Substances Data: 50548-46-4(Hazardous Substances Data)

Usage

Physical State

Solid

Color

White to yellowish

Odor

Slightly sweet

Uses

Building block in the synthesis of pharmaceuticals and agrochemicals

Biological Activity

Inhibitor of the enzyme indoleamine 2,3-dioxygenase (IDO)

Potential Applications

Drug candidate for the treatment of cancer and other inflammatory diseases

Hazards

Classified as an irritant to the skin, eyes, and respiratory system

Allergic Reactions

May cause allergic reactions in some individuals

Safety Precautions

Proper safety precautions should be taken when working with this chemical

Upstream product

• 106-54-7 p-Chlorothiophenol 
• 2032-35-1 Bromoacetaldehyde diethyl acetal 

Downstream Products

• 32969-26-9 3-bromo-5-chlorobenzo[b]thiophene 
• 28540-51-4 5-chlorobenzo[b]thiophene-2-carboxaldehyde 
• 155873-22-6 2-{2-[(4-chlorophenyl)thio]ethylidene} thiosemicarbazone 
• 105126-88-3 (4-chloro-phenylsulfanyl)-acetaldehyde 

Relevant articles and documents

2-(phenylthio)ethylidene derivatives as anti-Trypanosoma cruzi compounds: Structural design, synthesis and antiparasitic activity

Chagas disease is an illness caused by the protozoan parasite Trypanosoma cruzi. The current chemotherapy is based on benznidazole, and, in some countries, Nifurtimox, which is effective in the acute phase of the disease, but its efficacy in the chronic p

The phosphorescent compounds and organic light emitting diode device

A phosphorescent compound is disclosed. The phosphorescent compound represented by the following Chemical Formula 1, where X, Y, and Z are each selected from the group consisting of carbon and nitrogen, and when x, y, and z are all carbon, R is any one selected from the group consisting of carbazole, α-carboline, β-carboline, γ-carboline, fluorine, dibenzothiophene, dibenzofuran, triphenylsilane, tetraphenylsilane, pyridine, quinoline, isoquinoline, pyrimidine, diphenylphosphineoxide, and substituents thereof.

Synthesis, docking, and in vitro activity of thiosemicarbazones, aminoacyl-thiosemicarbazides and acyl-thiazolidones against Trypanosoma cruzi

A novel series of thiosemicarbazone and aminoacyl-thiazolidones derivatives were synthesized. Their structure suggests that these compounds could have anti-Trypanosoma cruzi activity. Biological evaluation indicates that some of these compounds are able t