329788-96-7Relevant articles and documents
Total synthesis of jadomycins B, S, T, and ILEVS1080
Yang, Xiaoyu,Yu, Biao
, p. 8431 - 8434 (2013/07/19)
Sweetening up jadomycin A: The first total synthesis of jadomycins B, S, T, and ILEVS1080 has been achieved, featuring construction of the unique 8H-benz[b]oxazolo[3,3-f]phenanthridine skeleton by biomimetic condensation of a quinone aldehyde with amino acid sodium salts and elaboration of the glycosides by Mitsunobu condensation (see figure). Copyright
Roles of the synergistic reductive O-methyltransferase GilM and of O-methyltransferase GilMT in the gilvocarcin biosynthetic pathway
Tibrewal, Nidhi,Downey, Theresa E.,Van Lanen, Steven G.,Ul Sharif, Ehesan,O'Doherty, George A.,Rohr, Juergen
, p. 12402 - 12405 (2012/09/05)
Two enzymes of the gilvocarcin biosynthetic pathway, GilMT and GilM, with unclear functions were investigated by in vitro studies using purified, recombinant enzymes along with synthetically prepared intermediates. The studies revealed GilMT as a typical
Synthesis of benzo[b]phenanthridines and related naturally occurring 2-aryl-1,4-naphthoquinones by palladium- and copper-catalyzed coupling of organostannanes with bromoquinones
De Frutos, Oscar,Atienza, Carmen,Echavarren, Antonio M.
, p. 163 - 171 (2007/10/03)
Syntheses of phenanthroviridone, gilvocarcin BE-12406X2, antibiotic WS 5995B, and a key intermediate for the synthesis of jadomycin are described, based on palladium- and copper-catalyzed coupling reactions of sterically hindered arylstannanes
