1262052-77-6Relevant articles and documents
Total synthesis of jadomycins B, S, T, and ILEVS1080
Yang, Xiaoyu,Yu, Biao
, p. 8431 - 8434 (2013)
Sweetening up jadomycin A: The first total synthesis of jadomycins B, S, T, and ILEVS1080 has been achieved, featuring construction of the unique 8H-benz[b]oxazolo[3,3-f]phenanthridine skeleton by biomimetic condensation of a quinone aldehyde with amino acid sodium salts and elaboration of the glycosides by Mitsunobu condensation (see figure). Copyright
Roles of the synergistic reductive O-methyltransferase GilM and of O-methyltransferase GilMT in the gilvocarcin biosynthetic pathway
Tibrewal, Nidhi,Downey, Theresa E.,Van Lanen, Steven G.,Ul Sharif, Ehesan,O'Doherty, George A.,Rohr, Juergen
experimental part, p. 12402 - 12405 (2012/09/05)
Two enzymes of the gilvocarcin biosynthetic pathway, GilMT and GilM, with unclear functions were investigated by in vitro studies using purified, recombinant enzymes along with synthetically prepared intermediates. The studies revealed GilMT as a typical
Total synthesis of jadomycin A and a carbasugar analogue of jadomycin B
Shan, Mingde,Sharif, Ehesan U.,O'Doherty, George A.
supporting information; experimental part, p. 9492 - 9495 (2011/02/22)
One's trash is another one's treasure: The first syntheses of jadomycin A and the carbasugar analogue of jadomycin B have been achieved in 6 and 20 longest linear steps, respectively. The key ring system of the aglycone was prepared by a 6π-electron elect
