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2,6-Dimethyl-3,5-dibromopyridine is a pyridine-based chemical compound characterized by the presence of two methyl groups and two bromine atoms. It has the chemical formula C7H6Br2N2 and is recognized for its versatile reactivity, allowing it to participate in a range of chemical reactions such as substitution, oxidation, and coupling. This unique structure and its properties render it a valuable component in the realms of organic synthesis and medicinal chemistry, particularly as a building block for the creation of pharmaceuticals, agrochemicals, and materials for research and development.

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  • 3430-34-0 Structure
  • Basic information

    1. Product Name: 2,6-Dimethyl-3,5-dibromopyridine
    2. Synonyms: 2-Chloro-5-Methyl-pyriMidin-4-ylaMine;Pyridine, 3,5-dibroMo-2,6-diMethyl-
    3. CAS NO:3430-34-0
    4. Molecular Formula: C7H7Br2N
    5. Molecular Weight: 264.96
    6. EINECS: N/A
    7. Product Categories: Heterocycle-Pyridine series
    8. Mol File: 3430-34-0.mol
  • Chemical Properties

    1. Melting Point: 46-57 °C
    2. Boiling Point: 240.2 °C at 760 mmHg
    3. Flash Point: 99.1 °C
    4. Appearance: /
    5. Density: 1.795 g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. PKA: 1.96±0.20(Predicted)
    10. CAS DataBase Reference: 2,6-Dimethyl-3,5-dibromopyridine(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2,6-Dimethyl-3,5-dibromopyridine(3430-34-0)
    12. EPA Substance Registry System: 2,6-Dimethyl-3,5-dibromopyridine(3430-34-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 3430-34-0(Hazardous Substances Data)

3430-34-0 Usage

Uses

Used in Pharmaceutical Industry:
2,6-Dimethyl-3,5-dibromopyridine serves as a key intermediate in the synthesis of various pharmaceuticals. Its ability to undergo multiple types of chemical reactions makes it instrumental in the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 2,6-Dimethyl-3,5-dibromopyridine is utilized as a precursor in the production of pesticides and other agrochemicals. Its reactivity and structural features contribute to the creation of compounds that can effectively address pest and disease control in agriculture.
Used in Research and Development:
2,6-Dimethyl-3,5-dibromopyridine is also employed as a building block in the synthesis of new materials for research and development purposes. Its unique chemical properties facilitate the exploration of novel applications and the advancement of scientific knowledge in material science and related fields.

Check Digit Verification of cas no

The CAS Registry Mumber 3430-34-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,3 and 0 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 3430-34:
(6*3)+(5*4)+(4*3)+(3*0)+(2*3)+(1*4)=60
60 % 10 = 0
So 3430-34-0 is a valid CAS Registry Number.

3430-34-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,5-Dibromo-2,6-dimethylpyridine

1.2 Other means of identification

Product number -
Other names 3.5-Dibrom-lutidin-(2.6)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3430-34-0 SDS

3430-34-0Relevant articles and documents

Synthesis method of 2, 6-dimethyl-3, 5-dibromopyridine

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Paragraph 0020; 0023; 0024; 0026, (2019/05/28)

The invention relates to the field of organic chemistry, in particular to a synthesis method of 2, 6-dimethyl-3, 5-dibromopyridine. The method includes following steps: (1), adding 2, 6-dimethyl-3-aminopyridine and acetic anhydride into a four-neck flask, rising temperature to backflow, and allowing thin-layer chromatography tracking reaction; (2), when temperature of reaction liquid in the step (1) is lowered to below 23 DEG C, dropwise adding liquid bromine, allowing reaction at 40-55 DEG C for 2-3h after dropwise adding is completed, adding water until all solid is dissolved, dropwise adding a sodium hydroxide solution, continuing reaction for 20-40min when a lot of precipitate is generated, suction-filtering, drying, and recrystallizing to obtain 2, 6-dimethyl-3-amino-5 bromopyridine;(3), adding 2, 6-dimethyl-3-amino-5 bromopyridine into a hydrogen bromide solution, dropwise adding a saturated sodium nitrite solution at the presence of cuprous bromide in a catalysis amount, controlling temperature to -3-4 DEG C, and allowing reaction for 2-3h to obtain 2, 6-dimethyl-3, 5-dibromopyridine.The method has the advantages of being mild in reaction condition, high in yield, easy-to-get in raw material, low in cost and short in process route and having industrialization prospect.

Synthetic method of 2,6-dimethyl-3,5-dibromopyridine

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Paragraph 0018; 0020; 0021; 0023; 0024; 0026, (2017/11/30)

The invention relates to the field of organic chemistry, in particular to a synthetic method of 2,6-dimethyl-3,5-dibromopyridine. The synthetic method comprises the following steps: (1) adding 2,6-dimethyl-3-aminopyridine and acetic anhydride into a four-necked flask, raising the temperature till backflow and performing thin layer chromatography tracking reaction; (2) after the temperature of reaction liquid in the step (1) is reduced to below 23 DEG C, dropwise adding liquid bromine, reacting for 2-3 hours at a temperature of 40-55 DEG C after the completion of dropwise adding, adding water till all solids are dissolved, then dropwise adding a sodium hydroxide solution, continuously reacting for 20-40 minutes after the generation of a large number of precipitates, performing suction filtration, drying and re-crystallizing to obtain 2,6-dimethyl-3-amino-5-bromopyridine; (3) adding the 2,6-dimethyl-3-amino-5-bromopyridine into a hydrogen bromide solution, dropwise adding a saturated sodium nitrite solution under the existence of a catalytic amount of cuprous bromide, controlling the temperature between 3 DEG C below zero and 4 DEG C and reacting for 2-3 hours to obtain the 2,6-dimethyl-3,5-dibromopyridine. The synthetic method provided by the invention is mild in reaction condition, high in yield, readily-available in raw material, lower in cost and short in process route and has an industrial prospect.

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