3430-33-9

Basic information

• Product Name: 3-AMINO-2,6-DIMETHYLPYRIDINE
• Synonyms: 2,6-Dimethyl-5-aminopyridine;3-AMINO-2,6-DIMETHYLPYRIDINE;2,6-DIMETHYL-3-PYRIDINAMINE;2,6-DIMETHYL-PYRIDIN-3-YLAMINE;2,6-dimethyl-3-pyridylamine;2,6-Dimethyl-3-Amino Pyridine;3-amino-2,6-lutidine;2,6-Dimethylpyridin-3-amine
• CAS NO: 3430-33-9
• Molecular Formula: C₇H₁₀N₂
• Molecular Weight: 122.17
• EINECS: 222-332-7
• Product Categories: Pyridine;Pyridines derivates
• Mol File: 3430-33-9.mol
• Article Data: 9

Chemical Properties

• Melting Point: 121-123°C
• Boiling Point: 230°C
• Flash Point: 230°C
• Appearance: /
• Density: 1.0289 (estimate)
• Vapor Pressure: 0.0621mmHg at 25°C
• Refractive Index: 1.5663 (estimate)
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 7.61±0.10(Predicted)
• Water Solubility: Insoluble in water.
• BRN: 2424
• CAS DataBase Reference: 3-AMINO-2,6-DIMETHYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-2,6-DIMETHYLPYRIDINE(3430-33-9)
• EPA Substance Registry System: 3-AMINO-2,6-DIMETHYLPYRIDINE(3430-33-9)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 20/21/22-36/37/38-41-37/38-22
• Safety Statements: 26-36/37/39-39
• RIDADR: UN2811
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 3430-33-9(Hazardous Substances Data)

Usage

Chemical Properties

Primrose yellow solid

Uses

3-Amino-2,6-dimethylpyridine is used as pharmaceutical intermediate.

InChI:InChI=1/C7H10N2/c1-5-3-4-7(8)6(2)9-5/h3-4H,8H2,1-2H3

Upstream product

• 1587660-46-5 C₁₁H₁₂N₂O₂ 
• 108-48-5 2,6-dimethylpyridine 
• 76809-28-4 3-(2,6-Dimethyl-pyridin-3-yl)-2,2-dimethyl-2,3-dihydro-benzo[e][1,3]oxazin-4-one 
• 4328-88-5 3-amino-2,6-dimethyl-isonicotinic acid 
• 15513-52-7 3-nitro-2,6-lutidine 

Downstream Products

• 62476-56-6 3-amino-2,6-dichloropyridine 
• 1256374-46-5 C₄₃H₆₁N₃O₆ 
• 3430-34-0 3,5-dibromo-2,6-dimethylpyridine 
• 912368-95-7 4-[(2,6-dimethylpiperidin-3-yl)amino]-2-phenylthieno[3,2-c]pyridine-7-carbonitrile 
• 1383735-49-6 1-(4-fluorophenyl)-5-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridine 
• 1383734-99-3 C₁₃H₁₀FN₃ 
• 52090-69-4 5-methyl-1H-pyrazolo[4,3-b]pyridine 
• 1383733-72-9 C₂₃H₃₂FN₅O₃ 
• 1383735-38-3 C₁₉H₂₂ClFN₄O₂ 
• 1383735-37-2 C₂HF₃O₂*C₁₈H₂₃FN₄O 

Relevant articles and documents

Pd/C-catalyzed transfer hydrogenation of aromatic nitro compounds using methanol as a hydrogen source

We describe the selective transfer hydrogenation of aromatic nitro compounds to anilines using Pd/C as a heterogeneous catalyst with methanol as a green reductant. Nitroarenes bearing both electron-releasing and electron-deficient groups are amenable to this method and enable the synthesis of corresponding arylamines in moderate to good selectivities including the synthesis of butamben, a local anesthictic drug molecule. This new concise protocol is simple, ligand-free and does not require the supply of external molecular hydrogen.

PYRIMIDINE AND PYRIDINE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF

Provided herein is a compound of formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, prodrug, codrug, cocrystal, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which is useful in treating, ameliorating or preventing influenza.

A mild, ferrocene-catalyzed C-H imidation of (hetero)arenes

A simple method for direct C-H imidation is reported using a new perester-based self-immolating reagent and a base-metal catalyst. The succinimide products obtained can be easily deprotected in situ (if desired) to reveal the corresponding anilines directly. The scope of the reaction is broad, the conditions are extremely mild, and the reaction is tolerant of oxidizable and acid-labile functionality, multiple heteroatoms, and aryl iodides. Mechanistic studies indicate that ferrocene (Cp2Fe) plays the role of an electron shuttle in the decomposition of the perester reagent, delivering a succinimidyl radical ready to add to an aromatic system.