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Isopropyl ethylcarbamate, also known as diethylcarbamazine, is a synthetic anthelmintic agent characterized by its ability to paralyze and kill parasitic worms within the body. It is primarily used as an insect repellent and in pharmaceutical applications for treating parasitic infections such as filariasis. Additionally, it serves as an effective ingredient in topical medications to alleviate itching and as a preservative in cosmetics and personal care products.

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  • 35601-81-1 Structure
  • Basic information

    1. Product Name: isopropyl ethylcarbamate
    2. Synonyms: isopropyl ethylcarbamate;Ethylcarbamic acid 1-methylethyl ester
    3. CAS NO:35601-81-1
    4. Molecular Formula: C6H13NO2
    5. Molecular Weight: 131.17292
    6. EINECS: 252-636-5
    7. Product Categories: N/A
    8. Mol File: 35601-81-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 183.8°Cat760mmHg
    3. Flash Point: 65°C
    4. Appearance: /
    5. Density: 0.935g/cm3
    6. Vapor Pressure: 0.756mmHg at 25°C
    7. Refractive Index: 1.415
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: isopropyl ethylcarbamate(CAS DataBase Reference)
    11. NIST Chemistry Reference: isopropyl ethylcarbamate(35601-81-1)
    12. EPA Substance Registry System: isopropyl ethylcarbamate(35601-81-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 35601-81-1(Hazardous Substances Data)

35601-81-1 Usage

Uses

Used in Pharmaceutical Industry:
Isopropyl ethylcarbamate is used as an anthelmintic drug for the treatment of parasitic infections, specifically targeting filariasis. It works by paralyzing and killing the worms, thereby reducing the symptoms and complications associated with the infection.
Used in Insect Repellent Industry:
As an insect repellent, isopropyl ethylcarbamate is used to deter insects and protect against bites that may transmit diseases or cause discomfort.
Used in Cosmetics and Personal Care Products:
Isopropyl ethylcarbamate is used as a preservative in cosmetics and personal care products to maintain their freshness and prevent spoilage, ensuring the safety and efficacy of these products for consumers.
Used in Topical Medications:
Isopropyl ethylcarbamate is used as an active ingredient in topical medications to provide relief from itching, which can be caused by various skin conditions or insect bites. Its effectiveness in alleviating itching contributes to the overall comfort and well-being of individuals using these medications.

Check Digit Verification of cas no

The CAS Registry Mumber 35601-81-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,6,0 and 1 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 35601-81:
(7*3)+(6*5)+(5*6)+(4*0)+(3*1)+(2*8)+(1*1)=101
101 % 10 = 1
So 35601-81-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H13NO2/c1-4-7-6(8)9-5(2)3/h5H,4H2,1-3H3,(H,7,8)

35601-81-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name propan-2-yl N-ethylcarbamate

1.2 Other means of identification

Product number -
Other names isopropyl N-ethylcarbamate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:35601-81-1 SDS

35601-81-1Downstream Products

35601-81-1Relevant articles and documents

Removal of flotation collector O-isopropyl-N-ethylthionocarbamate from wastewater

Dolenc, Darko,Kralj, Mojca Bavcon,Treb?e, Polonca,Wang, Zhe,Yao, Jun

, (2021/11/27)

Flotation collector O-isopropyl N-ethylthionocarbamate (IPETC) is widely used for separation of sulfide ores. Its removal from water by several oxidation processes was studied. Photocatalytic oxidation with air in the presence of iron salts, utilizing solar irradiation or artificial UV-A light is very efficient. Oxidation leads through the formation of O-isopropyl N-ethylcarbamate and several other reaction intermediates to total decomposition of organic compound in the final stage in 1 day. Similar results were obtained with a Fenton type oxidation with hydrogen peroxide and iron salts. Treatment with sodium hypochlorite yields mainly O-isopropyl N-ethylcarbamate. The formation of this compound in wastewaters can be of concern, since simple alkyl carbamates are cancer suspect agents.

Continuous Flow Synthesis of Urea-Containing Compound Libraries Based on the Piperidin-4-one Scaffold

Riesco-Domínguez, Alejandra,Blanco-Ania, Daniel,Rutjes, Floris P. J. T.

supporting information, p. 1312 - 1320 (2018/04/02)

The advantages of performing reactions in continuous flow vs. the classic batch processes render flow chemistry a suitable technique for library synthesis. Inspired by our recent work to create fluorine-containing nitrogen heterocycles and by the potentia

Nucleophilic Substitutions to Carbonic Acid Derivates. XII. Kinetics and Mechanism of the Reaction of N-Nitro-N-alkyl-urethanes with Primary Aliphatic Amines

Bacaloglu, R.,Prodan-Deac, Y.,Csunderlik, C.,Csomos, P.

, p. 10 - 20 (2007/10/02)

The aminolysis of N-alkyl-N-nitrourethanes takes place, as the kinetical studies demonstrate, by means of several consecutive steps.The nucleophilic attack of the amine (first step; reaction B), as well as the proton-transfere (second step; reaction C), are quick pre-equilibres, followed by the slow, rate-determining elimination of the nitramino-group (reaction D).During the deprotonation, an intermediate with two to the nitramino-group antiperiplanar orbitals is formed, providing the necessary mesomeric assistance of the elimination.

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