36138-76-8

Basic information

• Product Name: 5-Bromo-2-methylphenol
• Synonyms: 5-Bromo-2-methylphenol 95%;4-Bromo-2-hydroxytoluene, 5-Bromo-o-cresol;Phenol, 5-bromo-2-methyl-
• CAS NO: 36138-76-8
• Molecular Formula: C₇H₇BrO
• Molecular Weight: 187.04
• EINECS: 1533716-785-6
• Product Categories: Chemical Synthesis;Organic Building Blocks;Oxygen Compounds;Phenols;NULL;alcohol| alkyl bromide;Aromatic Phenols;Building Blocks;C6 to C8
• Mol File: 36138-76-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: 76-78°C
• Boiling Point: 241.8 °C at 760 mmHg
• Flash Point: 100.1 °C
• Appearance: /
• Density: 1.554 g/cm³
• Vapor Pressure: 0.0226mmHg at 25°C
• Refractive Index: 1.59
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 9.35±0.10(Predicted)
• CAS DataBase Reference: 5-Bromo-2-methylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-2-methylphenol(36138-76-8)
• EPA Substance Registry System: 5-Bromo-2-methylphenol(36138-76-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 1
• HazardClass: IRRITANT
• Hazardous Substances Data: 36138-76-8(Hazardous Substances Data)

Usage

Chemical Properties

Light yellow solid

InChI:InChI=1/C7H7BrO/c1-5-2-3-6(8)4-7(5)9/h2-4,9H,1H3

Upstream product

• 39478-78-9 5-bromo-2-methylaniline 
• 2835-95-2 amino-4 hydroxy-2 toluene 
• 7647-01-0 hydrogenchloride 
• 5532-69-4 4-bromo-2-(hydroxymethyl)phenol 
• 7732-18-5 water 
• 67-64-1 acetone 
• 95-48-7 ortho-cresol 

Downstream Products

• 67868-73-9 5-bromo-2-methylphenol methyl ether 
• 849726-21-2 5-bromo-4-iodo-2-methylphenol 
• 854778-42-0 4-bromo-1-(bromomethyl)-2-methoxybenzene 
• 858523-37-2 2-(4-bromo-2-methoxyphenyl)acetonitrile 
• 331273-58-6 2-(3-hydroxy-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 

Relevant articles and documents

A short synthesis of bisabolane sesquiterpenes

A facile total synthesis of three members of the bisabolane sesquiterpene family, namely (±)-curcumene, (±)-xanthorrhizol and (±)-curcuhydroquinone had been achieved in high overall yield. The synthesis used bromobenzene derivatives as starting materials.

8-Azabicyclo[3.2.1]octane derivatives

The present invention relates to a 8-azabicyclo[3.2.1]octane derivative of Formula I, wherein each of the substituents is given the definition as set forth in the specification and claims, or a pharmaceutically acceptable salt thereof or solvate thereof. The present invention also relates to a pharmaceutical composition comprising an 8-azabicyclo[3.2.1]octane derivative in admixture with one or more pharmaceutically acceptable auxiliaries and to the use of the 8-azabicyclo[3.2.1]octane derivative in therapy.

HETEROCYCLIC NON-PEPTIDE GNRH ANTAGONISTS

A compound of formula (I): wherein either B is absent and A and Z are the same or different and are each hydrogen, halogen, alkyl, hydroxy, alkoxy,-CN,-C(Rc)2OH,-N(Rd)C(=X)Rc,-C(=X)N(Rc)(Rd),-S(O)m-Rc,-N(Rc)(Rd)S(O)2,-S(O)2N(R c)(Rd),-N(Re)2, aryl optionally substituted with Ra or-O-aryl optionally substituted with Ra; or B is present and is-(CH2)n-,-C(Rb)2-or-O-, or B taken together with A or Z can be-C=C(Rb)-,-C(Rb)=C-,-CH2-CH(R b)-or-CH(Rb)-CH2-; D is-O-or-S(O) m,-; E is a bond or is-(CH2)n-,-N(R d)-,-(CH2)nN(Rd)-or-N(R d)(CH2)n-; F is-C(=X)-; G is-(CH2 )n-,-N(Rd)-,-(CH2)nN(R d)-or-N(Rd)(CH2)n; J is a bond,-O-,-N(RC)C(=X)-,-C(=X)N(Rc)-,-S(O)m,-,-N(Rc)S(O)m-,-S(O)nN(Rc)-,-N(Re)-or-N(Rg)(Rh); K is a bond, alkylene, cycloalkylene, cycloalkenylene, arylene, heterocycloalkylene, heterocycloalkylene or heteroarylene; and L is hydrogen or a terminal group; has therapeutic utility.