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3731-53-1

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3731-53-1 Usage

Description

4-Pyridinemethaneamine, also known as 4-(Aminomethyl)pyridine, is an organic compound with the chemical formula C6H8N2. It is a clear light brown oil at room temperature and is known for its derivatives that act as reversible inhibitors of various copper amine oxidases (CAOs). These properties make it a versatile compound with potential applications in different industries.

Uses

Used in Pharmaceutical Industry:
4-Pyridinemethaneamine is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its derivatives have the ability to inhibit copper amine oxidases, which are enzymes involved in the metabolism of biogenic amines. This makes it a promising candidate for the development of drugs targeting these enzymes, potentially leading to treatments for various diseases and conditions.
Used in Chemical Research:
As a clear light brown oil, 4-Pyridinemethaneamine serves as a valuable compound in chemical research and development. Its unique chemical properties allow it to be used in the synthesis of new molecules and the study of various chemical reactions. This contributes to the advancement of knowledge in the field of chemistry and the potential discovery of new applications for this compound.
Used in Material Science:
The chemical properties of 4-Pyridinemethaneamine, such as its ability to act as a reversible inhibitor of copper amine oxidases, make it a candidate for use in the development of new materials with specific properties. These materials could have applications in various industries, including electronics, coatings, and adhesives, where their unique properties can be harnessed for improved performance.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 21, p. 1927, 1973 DOI: 10.1248/cpb.21.1927

Check Digit Verification of cas no

The CAS Registry Mumber 3731-53-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,7,3 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 3731-53:
(6*3)+(5*7)+(4*3)+(3*1)+(2*5)+(1*3)=81
81 % 10 = 1
So 3731-53-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H8N2/c7-5-6-1-3-8-4-2-6/h1-4H,5,7H2/p+1

3731-53-1 Well-known Company Product Price

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  • Alfa Aesar

  • (L06345)  4-(Aminomethyl)pyridine, 97+%   

  • 3731-53-1

  • 25g

  • 281.0CNY

  • Detail
  • Alfa Aesar

  • (L06345)  4-(Aminomethyl)pyridine, 97+%   

  • 3731-53-1

  • 100g

  • 953.0CNY

  • Detail
  • Aldrich

  • (A65603)  4-(Aminomethyl)pyridine  98%

  • 3731-53-1

  • A65603-5G

  • 209.43CNY

  • Detail
  • Aldrich

  • (A65603)  4-(Aminomethyl)pyridine  98%

  • 3731-53-1

  • A65603-25G

  • 326.43CNY

  • Detail

3731-53-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Pyridinemethaneamine

1.2 Other means of identification

Product number -
Other names pyridin-4-ylmethanamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3731-53-1 SDS

3731-53-1Relevant articles and documents

A mild and selective Cu(II) salts-catalyzed reduction of nitro, azo, azoxy, N-aryl hydroxylamine, nitroso, acid halide, ester, and azide compounds using hydrogen surrogacy of sodium borohydride

Kalola, Anirudhdha G.,Prasad, Pratibha,Mokariya, Jaydeep A.,Patel, Manish P.

supporting information, p. 3565 - 3589 (2021/10/12)

The first mild, in situ, single-pot, high-yielding well-screened copper (II) salt-based catalyst system utilizing the hydrogen surrogacy of sodium borohydride for selective hydrogenation of a broad range of nitro substrates into the corresponding amine under habitancy of water or methanol like green solvents have been described. Moreover, this catalytic system can also activate various functional groups for hydride reduction within prompted time, with low catalyst-loading, without any requirement of high pressure or molecular hydrogen supply. Notably, this system explores a great potential to substitute expensive traditional hydrogenation methodologies and thus offers a greener and simple hydrogenative strategy in the field of organic synthesis.

Chemoselective reduction of nitro and nitrile compounds using an Fe3O4-MWCNTs?PEI-Ag nanocomposite as a reusable catalyst

Ansari, Sara,Khorshidi, Alireza,Shariati, Shahab

, p. 3554 - 3565 (2020/02/04)

Multi-walled carbon nanotubes (MWNTs) were modified with carboxylic acid functional groups (MWCNTs-(COOH)n) prior to decoration with Fe3O4 nanoparticles. A further modification step by polyethyleneimine (PEI) resulted in Fe3O4-MWCNTs?PEI which provided a suitable platform for coordination and in situ reduction of silver ions to obtain an Fe3O4-MWCNTs?PEI-Ag nanocomposite with highly dispersed Ag nanoparticles. The Fe3O4-MWCNTs?PEI-Ag hybrid material was characterized by various techniques such as Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), transmission electron microscopy (TEM), vibrating sample magnetometry (VSM), X-ray photoelectron spectroscopy (XPS) and thermogravimetric analysis (TGA), and was used as an efficient catalyst for chemoselective reduction of nitroaromatic and nitrile compounds to their corresponding amines in aqueous solution at ambient temperature. Nitrofurazone, a cytotoxic antibiotic, as a non-aromatic example was also reduced selectively at the nitro group without reduction of the other functionalities in the presence of Fe3O4-MWCNTs?PEI-Ag. The catalyst was magnetically recoverable and maintained its activity for at least six cycles without considerable loss of efficiency.

Preparation of nitrogen-doped carbon supported cobalt catalysts and its application in the reductive amination

Yuan, Ziliang,Liu, Bing,Zhou, Peng,Zhang, Zehui,Chi, Quan

, p. 347 - 356 (2019/01/24)

The use of non-noble metal catalysts with high activity is of great importance for organic transformations. Herein, nitrogen-doped carbon supported cobalt catalysts with high surface area up to 981.2 m2/g were prepared via the simple pyrolysis of cobalt coordinated organic polymers with silica as the hard template. The pyrolysis temperature showed a great effect on the structure and properties of the as-prepared catalysts. The Co@NC-800 catalyst with the pyrolysis temperature of 800 °C demonstrated a high activity for the selective reductive amination of carbonyl compounds to primary amines with ammonia and hydrogen. Structurally-diverse primary amines with yields in the range from 81.8% to 100% were attained under the optimal conditions. The Co@NC-800 catalyst could be reused without the loss of its activity. The Co@NC-800 catalyst demonstrated comparable activity as the reported heterogeneous noble metal catalysts.

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