391-78-6

Basic information

• Product Name: 6-FLUORO-4-HYDROXYQUINOLINE
• Synonyms: 4-HYDROXY-6-FLUOROQUINOLINE;6-FLUOROQUINOLIN-4-OL;6-FLUORO-4(1H)-QUINOLINONE;6-FLUORO-4-HYDROXYQUINOLINE;BUTTPARK 13\01-64
• CAS NO: 391-78-6
• Molecular Formula: C₉H₆FNO
• Molecular Weight: 163.15
• Product Categories: Heterocycles;Quinoline&Isoquinoline
• Mol File: 391-78-6.mol

Chemical Properties

• Melting Point: 221-223℃
• Boiling Point: 317℃
• Flash Point: 145℃
• Appearance: /
• Density: 1.366
• Vapor Pressure: 0.00858mmHg at 25°C
• Refractive Index: 1.571
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 4.07±0.40(Predicted)
• CAS DataBase Reference: 6-FLUORO-4-HYDROXYQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-FLUORO-4-HYDROXYQUINOLINE(391-78-6)
• EPA Substance Registry System: 6-FLUORO-4-HYDROXYQUINOLINE(391-78-6)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 391-78-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
6-Fluoro-4-hydroxyquinoline is used as a building block in organic synthesis for the preparation of various biologically active compounds. Its unique structure and properties make it a valuable component in the development of new drugs with potential therapeutic applications.
Used in Antibacterial Applications:
6-Fluoro-4-hydroxyquinoline is used as an antibacterial agent due to its antimicrobial properties. It has been studied for its potential to combat bacterial infections, offering a new avenue for the development of effective treatments against resistant strains.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 6-fluoro-4-hydroxyquinoline is utilized for its potential applications in drug discovery and development. Its unique chemical structure allows for the design and synthesis of novel compounds with potential therapeutic benefits.
Used in Organic Synthesis:
6-Fluoro-4-hydroxyquinoline serves as a key intermediate in the synthesis of complex organic molecules. Its presence in the molecular structure can influence the reactivity and selectivity of reactions, making it a valuable tool in the synthesis of pharmaceuticals and other bioactive compounds.
Used in Antimicrobial Research:
6-Fluoro-4-hydroxyquinoline is used in antimicrobial research to explore its potential as a new class of antimicrobial agents. Studies on its mechanism of action and efficacy against various pathogens can lead to the development of innovative treatments for infectious diseases.
Used in Drug Development:
In the realm of drug development, 6-fluoro-4-hydroxyquinoline is employed as a starting material or a structural component in the design of new pharmaceuticals. Its unique properties and potential interactions with biological targets make it a promising candidate for the creation of novel therapeutic agents.

InChI:InChI=1/C9H6FNO/c10-6-1-2-8-7(5-6)9(12)3-4-11-8/h1-5H,(H,11,12)

Upstream product

• 343-10-2 6-fluoro-4-hydroxy-quinoline-3-carboxylic acid 
• 318-35-4 ethyl 6-fluoro-4-hydroxy-3-quinoline-carboxylate 
• 26832-96-2 diethyl 2-(4-fluoroanilino)methylenemalonate 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 
• 371-40-4 4-fluoroaniline 
• 2033-24-1 cycl-isopropylidene malonate 

Downstream Products

• 391-77-5 4-Chloro-6-fluoroquinoline 
• 147006-10-8 4-fluoro-2-(2H-pyrazol-3-yl)aniline 
• 661463-17-8 4-bromine-6-fluoroquinoline 
• 482586-86-7 6-fluoroquinoline-4-carbaldehyde 
• 1093219-05-6 6-fluoro-4-(E)-styryl-quinoline 

Relevant articles and documents

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