40182-20-5Relevant articles and documents
METHOD FOR PRODUCING AMINE THROUGH REDUCTION OF AMIDE
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, (2022/01/08)
The present invention provides a method for producing primary amines and secondary amines, the method being characterized by reducing a primary amide or a secondary amide in the presence of a reducing agent and an organic metal halide of a group-2 element.
Solvent free acid catalysed direct N-alkylation of amines with alcohols using Al grafted MCM-41
Tayade, Kamlesh N.,Mishra, Manish,Munusamy,Somani, Rajesh S.
, p. 91 - 96 (2014/06/24)
The catalytic activity of Al grafted MCM-41 (Al-MS) was explored for solvent free acid catalysed direct N-alkylation of amines using alcohols as green alkylating agent to establish a clean method for synthesis of N-alkylated amines. The study revealed that acidity of Al-MS catalyst, reaction conditions and substrate's (amines and alcohols) nature are important factors influencing the N-alkylation reaction. The Al grafted MCM-41 with Si/Al molar ratio of 5 showed excellent activity for N-alkylation of amines with alcohols. The reusability of spent catalyst regenerated by simple washing with acetone was demonstrated for subsequent four reaction cycles.
