40527-42-2

Basic information

• Product Name: HELIOTROPINE DIETHYL ACETAL
• Synonyms: PIPERONAL DIETHYL ACETAL;HELOITROPIN DIETHYL ACETAL;HELIOTROPINE DIETHYL ACETAL;5-(diethoxymethyl)-3-benzodioxole;5-diethoxymethyl-1,3-benzodioxole;1,3-Benzodioxole, 5-(diethoxymethyl)-;1,3-Benzodioxole-5-carbaldehyde diethyl acetal;3,4-Methylenedioxybenzaldehyde diethyl acetal
• CAS NO: 40527-42-2
• Molecular Formula: C₁₂H₁₆O₄
• Molecular Weight: 224.25
• EINECS: 254-956-0
• Mol File: 40527-42-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 285.65°C (rough estimate)
• Flash Point: 98.9 °C
• Appearance: /
• Density: 1.0435 (rough estimate)
• Vapor Pressure: 0.00796mmHg at 25°C
• Refractive Index: 1.4560 (estimate)
• CAS DataBase Reference: HELIOTROPINE DIETHYL ACETAL(CAS DataBase Reference)
• NIST Chemistry Reference: HELIOTROPINE DIETHYL ACETAL(40527-42-2)
• EPA Substance Registry System: HELIOTROPINE DIETHYL ACETAL(40527-42-2)

Safety Data

• Hazardous Substances Data: 40527-42-2(Hazardous Substances Data)

Usage

General Description

Heliotropine diethyl acetal is a chemical compound with the molecular formula C12H16O2. It is a synthetic aroma compound used in perfumery and flavoring due to its sweet, vanilla-like scent. Heliotropine diethyl acetal can be found in various cosmetic and personal care products as a fragrance ingredient, as well as in food products for its flavoring properties. It is also used in the production of soaps, detergents, and other household products. The compound is typically colorless to pale yellow in appearance and is known for its strong, sweet odor.

InChI:InChI=1/C12H16O4/c1-3-13-12(14-4-2)9-5-6-10-11(7-9)16-8-15-10/h5-7,12H,3-4,8H2,1-2H3

Upstream product

• 120-57-0 piperonal 
• 122-51-0 orthoformic acid triethyl ester 
• 7647-01-0 hydrogenchloride 
• 64-17-5 ethanol 

Downstream Products

• 7145-99-5 5-methyl-1,3-benzodioxole 

Relevant articles and documents

Formation of Acetals and Ketals from Carbonyl Compounds: A New and Highly Efficient Method Inspired by Cationic Palladium

The development of a new, highly efficient, and simple method for masking carbonyl groups as acetals and ketals is described. This methodology relies on the nature of the palladium catalyst to direct the acetalization/ketalization reaction. This new protocol is mild and proceed with a very low catalyst loading at ambient temperatures. The method has been extended to a wide variety of different carbonyl compounds with various steric encumbrances to form the corresponding acetals and ketals in excellent yields.

A highly efficient and chemoselective method for acetalization of carbonyl compounds catalyzed by TiO2/SO42- solid superacid

Various types of aldehydes and ketones could be converted to their corresponding diethyl acetals with triethylorthoformate in the presence of TiO2/SO42- solid superacid in good to excellent yield under mild reaction conditions.

Solvent free protection of carbonyl group under microwave irradiation

Protection of aldehydes and ketones as acetals or dioxolanes catalysed by PTSA or KSF clay was readily achieved from orthoformates, 1,2-ethanediol or 2,2-dimethyl-1,3-dioxolane without solvent under microwave irradiation.