41345-70-4 Usage
Uses
Used in Pharmaceutical Industry:
3-Acetylsulfanylpropanoic acid is used as a synthetic intermediate for the development of new pharmaceutical compounds. Its unique structure allows for the creation of a wide range of molecules with potential therapeutic applications.
Used in Enzyme Inhibition:
3-Acetylsulfanylpropanoic acid is used as a potential enzyme inhibitor, particularly in the development of drugs targeting specific enzymes involved in various diseases. Its protected 3-mercaptopropionic acid structure makes it a promising candidate for this application.
Used in Chemical Synthesis:
As a synthetic intermediate, 3-acetylsulfanylpropanoic acid is used in the chemical synthesis of various compounds, including those with potential applications in the pharmaceutical, agrochemical, and materials science industries. Its versatility in chemical reactions makes it a valuable building block for the development of new molecules with specific properties and functions.
Purification Methods
Purify the propionic acid by distillation in a vacuum. It has max at 231nm ( 4200). It is a potential enzyme inhibitor [Noda et al. J Am Chem Soc 75 914 1953, Clegg et al. J Am Chem Soc 121 5319 2004, Clegg & Hutchinson Angew Chem, Int Edn 43 3716 2005]. [Beilstein 3 III 551, 3 IV 731.]
Check Digit Verification of cas no
The CAS Registry Mumber 41345-70-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,3,4 and 5 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 41345-70:
(7*4)+(6*1)+(5*3)+(4*4)+(3*5)+(2*7)+(1*0)=94
94 % 10 = 4
So 41345-70-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H8O3S/c1-4(6)9-3-2-5(7)8/h2-3H2,1H3,(H,7,8)
41345-70-4Relevant articles and documents
Transition state stabilization by micelles: Thiolysis of p-nitrophenyl alkanoates in cetyltrimethylammonium bromide micelles
Tee,Yazbeck
, p. 1100 - 1108 (2007/10/03)
Thiolysis of p-nitrophenyl esters (acetate to decanoate) by the anion of 2-mercaptoethanol (ME) is catalyzed by micelles of cetyltrimethylammonium bromide (CTAB) in aqueous solution. At fixed [ME], the observed rate constants (k(obs)) show saturation with
Effect of the α-methyl substituent on chemoselectivity in esterase-catalyzed hydrolysis of S-acetyl sulfanylalkanoates
Kumar, Ish,Jolly, Ravinder S.
, p. 207 - 209 (2008/02/11)
(Equation Presented) The isomeric compounds 1 and 3, which differ only in the position of a methyl substituent, give opposite chemoselectivities in an esterase-catalyzed hydrolysis reaction. The esterase was chemoselective for the oxoester in 1, but for the thiol ester group in 3. A high enantioselectivity was observed for both 1 and 3.
