4253-89-8

Basic information

• Product Name: ISOPROPYL DISULFIDE
• Synonyms: (i-C3H7S)2;2-(Isopropyldisulfanyl)propane;2,5-Dimethyl-3,4-dithiahexane;3,4-dithiahexane,2,5-dimethyl-;bis(1-methylethyl)disulfide;Diisopropyl disulphide;diisopropyldisulfide,2,5-dimethyl-3,4-dithiahexane;disulfide,bis(1-methylethyl)
• CAS NO: 4253-89-8
• Molecular Formula: C₆H₁₄S₂
• Molecular Weight: 150.31
• EINECS: 224-225-0
• Product Categories: sulfide Flavor;Organic Building Blocks;Sulfides/Disulfides;Sulfur Compounds;Alphabetical Listings;Flavors and Fragrances;I-L;Building Blocks;Chemical Synthesis;Organic Building Blocks;Sulfur Compounds
• Mol File: 4253-89-8.mol
• Article Data: 72

Chemical Properties

• Melting Point: -69°C
• Boiling Point: 175-176 °C(lit.)
• Flash Point: 65 °F
• Appearance: White to off-white to beige/Powder
• Density: 0.943 g/mL at 25 °C(lit.)
• Vapor Pressure: 1.35mmHg at 25°C
• Refractive Index: n20/D 1.4906(lit.)
• Storage Temp.: Flammables area
• CAS DataBase Reference: ISOPROPYL DISULFIDE(CAS DataBase Reference)
• NIST Chemistry Reference: ISOPROPYL DISULFIDE(4253-89-8)
• EPA Substance Registry System: ISOPROPYL DISULFIDE(4253-89-8)

Safety Data

• Hazard Codes: F,Xi
• Statements: 11-36/37/38-52-50
• Safety Statements: 9-16-29-33-36-26-61
• RIDADR: UN 1993 3/PG 2
• WGK Germany: 3
• HazardClass: 3.1
• PackingGroup: II
• Hazardous Substances Data: 4253-89-8(Hazardous Substances Data)

Usage

Chemical Properties

CLEAR COLOURLESS LIQUID

Occurrence

Reported found in guava fruit, French fried potato, cooked beef, grape brandy (Weinbrand) and durian (Durio zibethinus).

General Description

Isopropyl disulfide is a volatile sulfur compound that is reported to occur in Allium species.

InChI:InChI=1/C6H14S2/c1-5(2)7-8-6(3)4/h5-6H,1-4H3

Upstream product

• 828-26-2 hexamethyl-[1,3,5]trithiane 
• 75-30-9 2-iodo-propane 
• 2438-90-6 N,N'-dimethylthioperoxydicarbamic acid 
• 75-33-2 2-propanethiol 
• 67-64-1 acetone 
• 38739-06-9 S-isopropyl isopropanethiosulfinate 
• 609-73-4 o-nitroiodobenzene 
• 20607-43-6 sodium isopropanethiolate 
• 107-03-9 1-thiopropane 
• 13686-82-3 dithiosulfurous acid S,S'-diisopropyl ester 
• 1950-69-2 toluene-p-sulfonyl bromide 
• 537-14-4 dichlorophenolindophenol 
• 100244-53-9 (N-methyl-N-phenylcarbamoyl)sulfenyl chloride 
• 30044-59-8 (R)-2-((tert-butoxycarbonyl)amino)-3-(isopropyldisulfanyl)propanoic acid 

Downstream Products

• 40136-65-0 methyl isopropyl disulphide 
• 70398-84-4 1,2-Bisbenzene 
• 76757-65-8 C₂₄H₂₆PS⁽¹⁺⁾*BF₄^(1-) 
• 74542-66-8 1,2,3-tris(isopropylthio)benzene 
• 781-33-9 2-methyl-1,1-diphenylpropene 
• 35906-28-6 benzhydryl(isopropyl)sulfide 
• 101773-89-1 C₁₉H₂₄S₂ 
• 2386-41-6 triisopropyl tetrathiophosphate 
• 2432-47-5 S-isopropyl thiol-propionate 
• 75-33-2 2-propanethiol 
• 187737-37-7 propene 
• 14905-81-8 1-(isopropylthio)-4-methylbenzene 
• 4074-53-7 1-[4-(propan-2-ylsulfanyl)phenyl]ethan-1-one 
• 84264-99-3 4-(isopropylthio)benzaldehyde 

Relevant articles and documents

Substituted o-Aminophenols as Redox-Mediators in the Thiol Oxidation to Unsymmetrical Disulfides

A number of substituted o-aminophenols has been investigated as redox mediators of the thiol oxidation to disulfides. The electrooxidation of o-aminophenols leads to the corresponding o-iminobenzoquinones. These compounds react with thiols in the solution with a formation of disulfides. It was established that the use of 4,6-di-tert-butyl-2-(tert-butylamino)phenol as a redox mediator can reduce the overpotential of the thiol oxidation by 0.2-1.4 V depending on the nature of the coupling thiols. The unsymmetrical disulfides with alkyl, aryl, and heteroaryl substituents were obtained as the result of the indirect electrosynthesis.

A rapid, efficient and green procedure for transformation of alkyl halides/ tosylates to organochalcogens in water

A one-pot and efficient synthesis of dialkyl dichalcogenides (S, Se) in aqueous media under catalyst-free conditions using benzylic, allylic and primary halides with elemental sulfur and selenium has been developed. Also, this procedure was extended to preparation of trisulfides and triselenides from secondary and tertiary halides in same condition. In all cases, products can be obtained in good to excellent yield in short reactions time.

Dicationic Thiolate-Bridged Diruthenium Complexes for Catalytic Oxidation of Molecular Dihydrogen

Dicationic thiolate-bridged diruthenium complexes bearing sterically bulky alkane substituents on the thiolate ligands such as [Cp?Ru(μ-SiPr)2Ru(OH2)Cp?](OTf)2 have been found to work as effective catalysts toward oxidation of molecular dihydrogen into protons and electrons in protic solvents such as water and methanol. DFT calculations indicate that the sterically bulky alkane substituent in the complex plays an important role in facilitating the reaction step of the coordination of molecular dihydrogen.