426825-66-3

Basic information

• Product Name: 6-Bromo-2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine
• Synonyms: 6-Bromo-2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine;Imidazo[1,2-a]pyridine, 6-bromo-2-(4-fluorophenyl)-;6-bromo-2-(4-fluoropjhenyl)imidazo[1,2-a]pyridine
• CAS NO: 426825-66-3
• Molecular Formula: C₁₃H₈BrFN₂
• Molecular Weight: 291.1184232
• Mol File: 426825-66-3.mol

Chemical Properties

• Appearance: /
• Density: 1.55 g/cm³
• CAS DataBase Reference: 6-Bromo-2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Bromo-2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine(426825-66-3)
• EPA Substance Registry System: 6-Bromo-2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine(426825-66-3)

Safety Data

• Hazardous Substances Data: 426825-66-3(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry:
6-Bromo-2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine is used as a chemical intermediate for the synthesis of new pharmaceuticals. Its unique structural features allow it to interact with biological targets, making it a valuable compound for drug discovery and development.
Used in Oncology:
6-Bromo-2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine is used as a potential therapeutic agent in oncology. Its ability to interact with biological targets makes it a promising candidate for the development of new cancer treatments.
Used in Neurology:
6-Bromo-2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine is used as a potential therapeutic agent in neurology. Its interaction with biological targets may offer new avenues for the treatment of neurological disorders.
Used in Drug Synthesis:
6-Bromo-2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine is used as a key component in the synthesis of new drugs. Its unique structural features make it a valuable building block for the development of novel pharmaceuticals.
Used in Research and Investigation:
6-Bromo-2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine is used as a subject of ongoing research and investigation. Its synthesis and properties are being studied to better understand its potential applications and to develop new methods for its production and use.

Upstream product

• 1072-97-5 5-bromo-2-pyridylamine 
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• 329-79-3 1-(4-fluorophenyl)ethanone oxime 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 896885-34-0 1-(4-fluorophenyl)ethan-1-one-O-acetyl oxime 

Relevant articles and documents

CuCl2-catalyzed N[sbnd]O bond cleavage of oxime esters: Approach to imidazoheterocycles and furo[3,2-c]chromenyl fused imidazoles

An articulate approach to a diverse set of imidazoheterocycles in good to high yields via a copper-catalyzed aza-annulation of several oxime esters with a group of 2-amino-azaarenes was developed. The above cyclization reaction probably proceeds via a single electron transfer process which embodies a new technique for creating two new C[sbnd]N bonds for imidazole ring synthesis. Gratifyingly, the implementation of this chemistry could be further stretched to the synthesis of a novel class of fused imidazoles bearing a furo[3,2-c]chromene moiety via a sequential C[sbnd]N bond formation, followed by C(sp2)-H functionalization/5-endo-dig-oxacyclization (C[sbnd]C and C[sbnd]O bonds) of in situ produced fused imidazoles with cyclic enynones in the presence of copper(II) as a π-electrophilic Lewis acid catalyst.

Facile synthesis of new imidazo[1,2-a]pyridines carrying 1,2,3-triazoles via click chemistry and their antiepileptic studies

The present article reports the synthesis and anticonvulsant studies of new 2-arylimidazo[1,2-a]pyridines carrying suitably substituted 1,2,3-triazoles as well as their intermediates. The structures of newly synthesized compounds were confirmed by various

IMIDAZOPYRIDINE COMPOUNDS

The invention relates to compounds of formula (I): and their pharmaceutically acceptable salts and solvates, which are inhibitors of SSAO activity. The invention further relates to pharmaceutical compositions comprising these compounds and to the use of these compounds for the treatment or prevention of medical conditions wherein inhibition of SSAO activity is beneficial, such as inflammatory diseases and immune disorders.

Imidazo[1,2-a]pyridines and their use as pharmaceuticals

Imidazo[1,2-a]pyridines and their use as pharmaceuticals The present invention relates to derivatives of imidazo[1,2-a]pyridines of the formula (I), in which R, R1 to R4 and n have the meanings indicated in the claims, which modulate the transcription of

Imidazo[1,2-a]pyridines with potent activity against herpesviruses

Synthesis of a series of 2-aryl-3-pyrimidyl-imidazo[1,2-a]pyridines with potent activity against herpes simplex viruses is described. Synthetic approaches allowing for variation of the 2-aryl, 3-heteroaryl as well as other imidazopyridine substituents are

Synthesis of polysubstituted imidazo[1,2-a]pyridines via microwave-assisted one-pot cyclization/Suzuki coupling/palladium-catalyzed heteroarylation

(Chemical Equation Presented) A new and efficient method for the synthesis of 2,3,6-trisubstituted imidazo[1,2-a]pyridine derivatives using a microwave-assisted one-pot, two-step Suzuki/heteroarylation or one-pot, three-step cyclization/Suzuki/heteroarylation was developed. Polysubstituted compounds are obtained in good yield from 2-amino-5-halogenopyridines, 2-halogenocarbonyl derivatives, boronic acids, and heteroaryl bromides.

(Hetero)arylation of 6-halogenoimidazo[1,2-a]pyridines differently substituted at C(2): Influence of the 2-substituent on the Suzuki cross-coupling reaction

We previously reported that reactivity towards the Suzuki cross-coupling reaction of 3-iodoimidazo[1,2-a]pyridines substituted at C(2) is largely influenced by the nature of this 2-substituent. Hence, with the aim to expand the scope of this coupling proc