Welcome to LookChem.com Sign In|Join Free

Cas Database

4282-34-2

4282-34-2

Identification

Synonyms:Dimethyl 2,5-thiophenedicarboxylate;2,5-Thiophenedicarboxylicacid, dimethyl ester (6CI,7CI,8CI,9CI);2,5-Bismethoxycarbonylthiophene;

Post Buying Request Now

Safety information and MSDS view more

  • Signal Word:no data available

  • Hazard Statement:no data available

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

  • Fire-fighting measures: Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

  • Exposure controls/personal protection:Occupational Exposure limit valuesBiological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

Supplier and reference price view more

  • Manufacture/Brand
  • Product Description
  • Packaging
  • Price
  • Delivery
  • Purchase
  • Manufacture/Brand:SynQuest Laboratories
  • Product Description:Dimethyl thiophene-2,5-dicarboxylate
  • Packaging:5 g
  • Price:$ 794
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:SynQuest Laboratories
  • Product Description:Dimethyl thiophene-2,5-dicarboxylate
  • Packaging:1 g
  • Price:$ 199
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Matrix Scientific
  • Product Description:Dimethyl thiophene-2,5-dicarboxylate
  • Packaging:1g
  • Price:$ 300
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Matrix Scientific
  • Product Description:Dimethyl thiophene-2,5-dicarboxylate
  • Packaging:0.500g
  • Price:$ 240
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Crysdot
  • Product Description:Dimethylthiophene-2,5-dicarboxylate 97%
  • Packaging:5g
  • Price:$ 340
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Biosynth Carbosynth
  • Product Description:Dimethyl thiophene-2,5-dicarboxylate
  • Packaging:5 g
  • Price:$ 868
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Biosynth Carbosynth
  • Product Description:Dimethyl thiophene-2,5-dicarboxylate
  • Packaging:2 g
  • Price:$ 434
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Biosynth Carbosynth
  • Product Description:Dimethyl thiophene-2,5-dicarboxylate
  • Packaging:1 g
  • Price:$ 255
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Biosynth Carbosynth
  • Product Description:Dimethyl thiophene-2,5-dicarboxylate
  • Packaging:500 mg
  • Price:$ 150
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Biosynth Carbosynth
  • Product Description:Dimethyl thiophene-2,5-dicarboxylate
  • Packaging:250 mg
  • Price:$ 85
  • Delivery:In stock
  • Buy Now

Relevant articles and documentsAll total 2 Articles be found

Synthesis of 2-thiophenecarboxylic and 2,5-thiophenedicarboxylic acid esters via the reaction of thiophenes with the CCl4-ROH reagent in the presence of vanadium, iron, and molybdenum catalysts

Khusnutdinov,Shchadneva,Baiguzina,Mukminov,Mayakova,Smirnov,Dzhemilev

experimental part, p. 471 - 478 (2010/03/31)

2-Thiophenecarboxylic and 2,5-thiohenedicarboxylic acid esters were synthesized via the reaction of thiophene with the CCl4-ROH-catalyst system, with a total yield of 44-85%. A possible reaction scheme includes the successive steps of alkylation of thiophene with carbon tetrachloride, leading to 2-trichloromethylthiophene, and alcoholysis of the product giving the corresponding 2-thiophenecarboxylate. The best catalysts for this reaction are VO(acac)2, Fe(acac)3, and Mo(CO)6.

Process route upstream and downstream products

Process route

methanol
67-56-1

methanol

tetrachloromethane
56-23-5

tetrachloromethane

thiophene-2-carboxylic acid methyl ester
5380-42-7

thiophene-2-carboxylic acid methyl ester

Dimethyl thiophene-2,5-dicarboxylate
4282-34-2

Dimethyl thiophene-2,5-dicarboxylate

Conditions
Conditions Yield
With iron(III)-acetylacetonate; at 140 ℃; for 6h; Inert atmosphere; Autoclave;
44%
9%
2,5-dibromothiophen
3141-27-3

2,5-dibromothiophen

carbon monoxide
201230-82-2

carbon monoxide

Thiophene-2,5-dicarboxylic acid
4282-31-9

Thiophene-2,5-dicarboxylic acid

Dimethyl thiophene-2,5-dicarboxylate
4282-34-2

Dimethyl thiophene-2,5-dicarboxylate

Conditions
Conditions Yield
With methanol; tert-Amyl alcohol; sodium hydride; cobalt(II) acetate; In tetrahydrofuran; at 40 ℃; for 54h; under 760 Torr; Irradiation;
55%
17%
methanol
67-56-1

methanol

2,5-dibromothiophen
3141-27-3

2,5-dibromothiophen

carbon monoxide
201230-82-2

carbon monoxide

Thiophene-2,5-dicarboxylic acid
4282-31-9

Thiophene-2,5-dicarboxylic acid

Dimethyl thiophene-2,5-dicarboxylate
4282-34-2

Dimethyl thiophene-2,5-dicarboxylate

Conditions
Conditions Yield
With tert-Amyl alcohol; sodium hydride; cobalt(II) acetate; In tetrahydrofuran; at 40 ℃; for 54h; under 760 Torr; Irradiation;
17%
55%
acrylic acid methyl ester
292638-85-8,9003-21-8,96-33-3

acrylic acid methyl ester

Thiophen-2,4-dicarbonsaeure-dimethylester
6520-81-6

Thiophen-2,4-dicarbonsaeure-dimethylester

Dimethyl thiophene-2,5-dicarboxylate
4282-34-2

Dimethyl thiophene-2,5-dicarboxylate

Conditions
Conditions Yield
With sulfur; at 200 ℃;
acrylic acid methyl ester
292638-85-8,9003-21-8,96-33-3

acrylic acid methyl ester

Thiophen-2,4-dicarbonsaeure-dimethylester
6520-81-6

Thiophen-2,4-dicarbonsaeure-dimethylester

Dimethyl thiophene-2,5-dicarboxylate
4282-34-2

Dimethyl thiophene-2,5-dicarboxylate

Conditions
Conditions Yield
at 150 - 200 ℃;
Dimethyl thiophene-2,5-dicarboxylate
4282-34-2

Dimethyl thiophene-2,5-dicarboxylate

thiophene-2-carboxylic acid methyl ester
5380-42-7

thiophene-2-carboxylic acid methyl ester

Conditions
Conditions Yield
Dimethyl thiophene-2,5-dicarboxylate; With sodium hydroxide; In water; for 2h; Reflux; Large scale;
In N,N-dimethyl-formamide; at 150 ℃; for 2h; Large scale;
1410 g
Dimethyl thiophene-2,5-dicarboxylate
4282-34-2

Dimethyl thiophene-2,5-dicarboxylate

Thiophene-2,5-dicarboxylic acid
4282-31-9

Thiophene-2,5-dicarboxylic acid

Conditions
Conditions Yield
With sulfuric acid; In water; at 60 ℃; for 2h; Large scale;
1679 g
Dimethyl thiophene-2,5-dicarboxylate
4282-34-2

Dimethyl thiophene-2,5-dicarboxylate

2-thiophenylcarboxylic acid
527-72-0

2-thiophenylcarboxylic acid

Conditions
Conditions Yield
With sodium chloride; In water; dimethyl sulfoxide; at 150 - 180 ℃; for 5h; Large scale;
Dimethyl thiophene-2,5-dicarboxylate
4282-34-2

Dimethyl thiophene-2,5-dicarboxylate

(S)-1-(4-methylphenyl)ethylamine
27298-98-2

(S)-1-(4-methylphenyl)ethylamine

(S)-5-(1-p-Tolyl-ethylcarbamoyl)-thiophene-2-carboxylic Acid Methyl Ester
709613-20-7

(S)-5-(1-p-Tolyl-ethylcarbamoyl)-thiophene-2-carboxylic Acid Methyl Ester

Conditions
Conditions Yield
Dimethyl thiophene-2,5-dicarboxylate; With thionyl chloride; N,N-dimethyl-formamide; In dichloromethane; at 80 ℃; for 1h;
(S)-1-(4-methylphenyl)ethylamine; With triethylamine; In dichloromethane;
71%
Dimethyl thiophene-2,5-dicarboxylate
4282-34-2

Dimethyl thiophene-2,5-dicarboxylate

(R)-1-phenyl-ethyl-amine
3886-69-9

(R)-1-phenyl-ethyl-amine

(R)-5-(1-Phenyl-ethylcarbamoyl)-thiophene-2-carboxylic Acid Methyl Ester
709613-19-4

(R)-5-(1-Phenyl-ethylcarbamoyl)-thiophene-2-carboxylic Acid Methyl Ester

Conditions
Conditions Yield
Dimethyl thiophene-2,5-dicarboxylate; With thionyl chloride; In tetrahydrofuran; thionyl chloride; for 72h; Heating / reflux;
(R)-1-phenyl-ethyl-amine; With triethylamine; In tetrahydrofuran; at -15 - 20 ℃; for 17h;
83%

Global suppliers and manufacturers

Global( 12) Suppliers
  • Company Name
  • Business Type
  • Contact Tel
  • Emails
  • Main Products
  • Country
  • Finetech Industry Limited
  • Business Type:Trading Company
  • Contact Tel:86-27-87465837
  • Emails:sales@finetechnology-ind.com
  • Main Products:29
  • Country:China (Mainland)
  • Antimex Chemical Limied
  • Business Type:Lab/Research institutions
  • Contact Tel:0086-21-50563169
  • Emails:anthony@antimex.com
  • Main Products:163
  • Country:China (Mainland)
  • Amadis Chemical Co., Ltd.
  • Business Type:Lab/Research institutions
  • Contact Tel:86-571-89925085
  • Emails:sales@amadischem.com
  • Main Products:1
  • Country:China (Mainland)
  • Hangzhou KieRay Chem Co.,Ltd.
  • Business Type:Lab/Research institutions
  • Contact Tel:+86-0571-56123425
  • Emails:purchase@kieraychem.com
  • Main Products:1
  • Country:China (Mainland)
  • Jinan Great Chemical Co.,Ltd.
  • Business Type:Lab/Research institutions
  • Contact Tel:+86-531-58668191 58668193 58668196 58661173
  • Emails:sale001@chemgreat.com
  • Main Products:1
  • Country:China (Mainland)
close
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 4282-34-2
Post Buying Request Now
close
Remarks: The blank with*must be completed