4440-01-1Relevant articles and documents
Mechanistic Study of Pd/NHC-Catalyzed Sonogashira Reaction: Discovery of NHC-Ethynyl Coupling Process
Eremin, Dmitry B.,Boiko, Daniil A.,Kostyukovich, Alexander Yu.,Burykina, Julia V.,Denisova, Ekaterina A.,Anania, Mariarosa,Martens, Jonathan,Berden, Giel,Oomens, Jos,Roithová, Jana,Ananikov, Valentine P.
, p. 15672 - 15681 (2020)
The product of a revealed transformation—NHC-ethynyl coupling—was observed as a catalyst transformation pathway in the Sonogashira cross-coupling, catalyzed by Pd/NHC complexes. The 2-ethynylated azolium salt was isolated in individual form and fully char
A Germylene/Borane Lewis Pair and the Remarkable C=O Bond Cleavage Reaction toward Isocyanate and Ketone Molecules
Li, Jiancheng,Li, Bin,Liu, Rui,Jiang, Liuyin,Zhu, Hongping,Roesky, Herbert W.,Dutta, Sayan,Koley, Debasis,Liu, Weiping,Ye, Qingsong
, p. 14499 - 14503 (2016)
A germylene/borane Lewis pair (2) was prepared from a 1,1-carboboration of amidinato phenylethynylgermylene (1) by B(C6F5)3. Compound 2 reacted with iPrNCO and (4-MeOC6H4)C(O)Me, respectively, with cleavage of the C=O double bond. In the first instance, O and iPrNC insert separately into the Ge?B bond to yield a GeBC2O-heterocycle (3) and a GeBC3-heterocycle (4). In the second case (4-MeOC6H4)(Me)C inserts into the Ge?N bond of 2 while O is incorporated in the Ge?B bond to form a Ge-centered spiroheterocycle (5). The reaction of 2 with tBuNC to give 6, which has almost the same structure as 4, proved the formation of the isonitrile during transformation from 2 and iPrNCO to 3 and 4. The kinetic study of the reaction of 2 and iPrNCO gave evidence of proceeding through a GeBC3O-heterocycle intermediate. In addition, a DFT study was performed to elucidate the reaction mechanism.
Dibridgehead diphosphines that turn themselves inside out
Stollenz, Michael,Barbasiewicz, Michal,Nawara-Hultzsch, Agnieszka J.,Fiedler, Tobias,Laddusaw, Ryan M.,Bhuvanesh, Nattamai,Gladysz, John A.
, p. 6647 - 6651 (2011)
Molecular contortionists can lurk in unexpected places. The title compounds undergo equilibria that appear to involve straightforward pyramidal inversions at the phosphorus atoms, but in reality the stereoisomers interconvert by turning themselves inside
Synthesis, antitumor activity, and cytotoxicity of 4-substituted 1-benzyl-5-diphenylstibano-1H-1,2,3-triazoles
Yamada, Mizuki,Takahashi, Tsutomu,Hasegawa, Mai,Matsumura, Mio,Ono, Kanna,Fujimoto, Ryota,Kitamura, Yuki,Murata, Yuki,Kakusawa, Naoki,Tanaka, Motohiro,Obata, Tohru,Fujiwara, Yasuyuki,Yasuike, Shuji
supporting information, p. 152 - 154 (2017/12/06)
Trisubstituted 5-organostibano-1H-1,2,3-triazoles (3a–f) were synthesized by the Cu-catalyzed azide-alkyne cycloaddition of various ethynylstibanes (1) with benzylazide (2) in the presence of CuBr (5 mol%) under aerobic conditions. The reaction of 5-stiba
