446-11-7

Basic information

• Product Name: 4-Fluoro-3-nitrotoluene
• Synonyms: 3-nitro-4-fluorotoluol;2-Fluoro-5-methylnitrobenzene, 1-Fluoro-4-methyl-2-nitrobenzene;4-Fluoro-3-nitrotoluene, 97+%;3-NITRO-4-FLUOROTOLUENE;4-FLUORO-3-NITROTOLUENE;TIMTEC-BB SBB008624;1-Fluoro-4-methyl-2-nitrobenzene;2-Fluoro-5-methylnitrobenzene
• CAS NO: 446-11-7
• Molecular Formula: C₇H₆FNO₂
• Molecular Weight: 155.13
• Product Categories: Fluorinated benzene series;Fluorin-contained toluene series;blocks;FluoroCompounds;NitroCompounds;Aromatic Hydrocarbons (substituted) & Derivatives;Halogen toluene
• Mol File: 446-11-7.mol

Chemical Properties

• Melting Point: 28 °C
• Boiling Point: 241 °C
• Flash Point: 22 °C
• Appearance: Red-brown/Liquid
• Density: 1.262
• Vapor Pressure: 0.0612mmHg at 25°C
• Refractive Index: 1.524
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-Fluoro-3-nitrotoluene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Fluoro-3-nitrotoluene(446-11-7)
• EPA Substance Registry System: 4-Fluoro-3-nitrotoluene(446-11-7)

Safety Data

• Hazard Codes: Xi,C
• Statements: 20/21/22-36/37/38-34
• Safety Statements: 26-36-45-36/37/39
• HazardClass: 6.1
• Hazardous Substances Data: 446-11-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-Fluoro-3-nitrotoluene is used as a key intermediate for the synthesis of various pharmaceutical compounds. Its presence in the molecular structure of these compounds can influence their pharmacological properties, such as potency, selectivity, and metabolic stability, making it a valuable component in drug development.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Fluoro-3-nitrotoluene serves as an essential intermediate in the production of pesticides and other agrochemicals. Its chemical properties allow for the creation of effective compounds designed to protect crops from pests and diseases, thereby contributing to increased agricultural productivity.
Used in Dye and Pigment Production:
4-Fluoro-3-nitrotoluene is also utilized as a starting material in the manufacture of dyes and pigments. Its unique combination of fluorine and nitro groups can impart specific color characteristics and stability to the final products, which is crucial for applications in textiles, plastics, and other industries that rely on colorants.
Safety and Handling:
Given its toxic nature and potential to cause irritation to the skin, eyes, and respiratory system, 4-Fluoro-3-nitrotoluene is classified as a hazardous material. It is imperative to handle, store, and dispose of 4-Fluoro-3-nitrotoluene according to stringent safety protocols and regulations to minimize risks to human health and the environment.

InChI:InChI=1/C7H6FNO2/c1-5-2-3-6(8)7(4-5)9(10)11/h2-4H,1H3

Upstream product

• 352-32-9 p-fluorotoluene 
• 24920-35-2 4-methyl-2-nitrobenzenediazonium 
• 56-23-5 tetrachloromethane 
• 7697-37-2 nitric acid 
• 89-62-3 4-methyl-2-nitroaniline 
• 452-84-6 3-amino-4-fluorotoluene 

Downstream Products

• 119-33-5 4-methyl-2-nitrophenol 
• 19199-62-3 2-Chlor-3-(2-nitro-4-methyl-phenoxy)-benzoesaeure 
• 116940-73-9 N-(4-methyl-2-nitrophenyl)piperidine-2-carboxylic acid 
• 127827-45-6 N-4'-Methyl-2'-nitrophenyl-1,2,3,4-tetrahydroisoquinoline 
• 15017-52-4 4-(bromomethyl)-1-fluoro-2-nitrobenzene 
• 89-62-3 4-methyl-2-nitroaniline 
• 4600-08-2 4,N-dimethyl-2-nitroaniline 
• 173843-49-7 ethyl 4-(4-methyl-2-nitroanilino)-1-piperidinecarboxylate 
• 912284-87-8 2-[methyl-(4-methyl-2-nitro-phenyl)-amino]-ethanol 
• 912284-73-2 2-[(2-amino-4-methyl-phenyl)-methyl-amino]-ethanol 
• 107618-24-6 ethyl 4-(4-methyl-2-aminoanilino)-1-piperidinecarboxylate 

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