4571-24-8

Basic information

• Product Name: 1,4-Dibromo-2,5-dichlorobenzene
• Synonyms: 1,4-Dibromo-2,5-dichlorobenzene;Benzene,1,4-dibromo-2,5-dichloro-;1,4-Dibromo-2,5-dichlorobenzen
• CAS NO: 4571-24-8
• Molecular Formula: C₆H₂Br₂Cl₂
• Molecular Weight: 304.79408
• Mol File: 4571-24-8.mol

Chemical Properties

• Melting Point: 148-150 °C
• Boiling Point: 292.9°C at 760 mmHg
• Flash Point: 141.9°C
• Appearance: /
• Density: 2.091g/cm³
• Vapor Pressure: 0.00312mmHg at 25°C
• Refractive Index: 1.623
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1,4-Dibromo-2,5-dichlorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Dibromo-2,5-dichlorobenzene(4571-24-8)
• EPA Substance Registry System: 1,4-Dibromo-2,5-dichlorobenzene(4571-24-8)

Safety Data

• Hazardous Substances Data: 4571-24-8(Hazardous Substances Data)

Usage

Uses

Used in Pesticide and Insecticide Industry:
1,4-Dibromo-2,5-dichlorobenzene is utilized as a pesticide and insecticide due to its ability to control and eliminate various pests and insects, thereby protecting crops and reducing damage to agricultural yields.
Used in Dye and Pigment Production:
In the dye and pigment industry, 1,4-Dibromo-2,5-dichlorobenzene is employed as a key intermediate in the synthesis of various dyes and pigments, contributing to the coloration and stability of these products.
Used in Disinfectant and Deodorizer Manufacturing:
1,4-Dibromo-2,5-dichlorobenzene is used in the production of disinfectants and deodorizers, where its antimicrobial properties help to sanitize surfaces and control odors in various settings, including households and commercial spaces.
However, it is important to note that exposure to 1,4-Dibromo-2,5-dichlorobenzene can result in irritation to the skin, eyes, and respiratory tract. Additionally, due to its toxicity and persistence in the environment, it is considered a potential environmental hazard, necessitating careful handling and disposal to minimize ecological impact.

InChI:InChI=1/C6H2Br2Cl2/c7-3-1-5(9)4(8)2-6(3)10/h1-2H

Upstream product

• 106-46-7 para-dichlorobenzene 
• 95-82-9 2,5 dichloroaniline 
• 31604-30-5 1,2,4,5-tetrabromo-3,6-dichlorobenzene 
• 7664-93-9 sulfuric acid 
• 7726-95-6 bromine 
• 7697-37-2 nitric acid 
• 89244-49-5 C₆Br₂Cl₂Li₂ 
• 71-43-2 benzene 
• 106-95-6 allyl bromide 
• 626-43-7 3,5-Dichloroaniline 

Downstream Products

• 1048656-93-4 C₁₄H₈Cl₂S₂ 
• 1048656-94-5 C₂₂H₁₂Cl₂S₄ 
• 491612-78-3 C₄₆H₃₀ 

Relevant articles and documents

A method for the synthesis of 2, 5 - dichlorophenol (by machine translation)

The invention relates to a 2, 5?Dichiorophenol synthetic method, which belongs to the technical field of the synthesis of the key intermediate chamber. The invention is composed of a pure chlorization generated 1, 2, 4?Trichlorobenzene and santochlor is easy to separate, thereby avoiding the difficulties caused by the separating of the high production cost and low production efficiency; because the 1, 2, 4?Trichlorobenzene and to two chiorophenoxy can be obtained respectively 2, 5?Dichiorophenol, utilization rate of raw materials is high, thereby avoiding the waste of the by-product, so that the production cost is greatly reduced. In addition, the two paradichlorbenzene through two different method to obtain 2, 5?Dichiorophenol. The synthesis technique of this invention is simple, the production cost is low, the utilization rate of raw materials is high, and the craft there are few by-products, less generation of three wastes, is more suitable for large-scale industrial production. (by machine translation)

Bromination of aromatic compounds using an Fe2O 3/zeolite catalyst

The catalytic bromination of non-activated aromatic compounds has been achieved using an Fe2O3/zeolite catalyst system. FeBr 3 was identified as the catalytic species, formed in situ from HBr and Fe2O3. The catalyst was easy-to-handle and cost effective and could also be recycled. The reaction system was also amenable to the one-pot sequential bromination/C-C bond formation of benzene.

Aromatic allylation via diazotization: Metal-free C-C bond formation

A new method for the synthesis of allyl aromatic compounds not involving any metal-containing reagent or catalyst has been developed. Arylamines substituted with a large number of different substituents were converted via diazotizative deamination with tert-butyl nitrite in allyl bromide and acetonitrile to the corresponding allyl aromatic compounds. The allylation reaction was found to be suitable for larger scale synthesis due to short reaction times, a nonextractive workup, and robustness toward moisture, air, and type of solvent.

THE DILITHIATION MECHANISM IN THE REACTIONS OF POLYHALOARENES AS DI-ARYNE EQUIVALENTS

The preparation of certain 1,4-dilithio-tetrahaloarenes is described; they react with electrophiles at low temperatures or form arynes at higher temperatures.

Alkyl Nitrite-Metal Halide Deamination Reactions. 7. Synthetic Coupling of Electrophilic Bromination with Substitutive Deamination for Selective Synthesis of Multiply Brominated Aromatic Compounds from Arylamines

Aromatic amines undergo substitution with copper(II)bromide that is in competition with substitutive deamination when these reactions are performed with tert-butyl nitrite.Except for the exceptionally reactive 4-substituted 1-aminonaphthalenes,which undergo selective bromine substitution at the 1- and 2-positions in relatively high isolated yields,rates for oxidative bromination and substitutive deamination are not sufficiently different that selective multiple bromination can be achieved.Oxidative bromination of N,N-dimethylaniline by copper(II)bromide occurs with partial dealkylation,and nitration products are observed from reactions performed with copper(II)bromide and tert-butyl nitrite.Implications of these results for the successful utilization of copper(II)bromide/tert-butyl nitrite combinations in substitutive deamination reactions of aromatic amines are discussed.Multiply brominated aromatic compounds are produced from aromatic amines in high yield through treatment of the aromatic amine with the combination of molecular bromine and catalytic quantities of copper(II)bromide and,following a normally brief time delay,with tert-butyl nitrite.All unsubstituted aromatic ring positions ortho and para to the amino group,as well as the position of the amino group,are substituted by bromine.The only observed byproducts from use of this procedure (usually 2percent yield) are the partially brominated benzene derivatives.