4765-77-9

Basic information

• Product Name: 6-Chloropyrimidin-4(3H)-one
• Synonyms: 6-CHLOROPYRIMIDIN-4(3H)-ONE;6-CHLOROPYRIMIDIN-4-OL;6-Chloro-4-pyrimidinol;6-CHLORO-4-HYDROXYPYRIMIDINE;4(1H)-Pyrimidinone, 6-chloro- (9CI);6-Chloro-4(1H)-Pyrimidinone;6-CHLORO-4-HYDROXYPYRIMIDINE,98%;6-chloropyrimidin-4(1H)-one
• CAS NO: 4765-77-9
• Molecular Formula: C₄H₃ClN₂O
• Molecular Weight: 130.53
• EINECS: 1533716-785-6
• Product Categories: PYRIMIDINE;APIs & Intermediate;Nucleotides and Nucleosides;Bases & Related Reagents;Nucleotides;Heterocycles;Heterocycle-Pyrimidine series
• Mol File: 4765-77-9.mol

Chemical Properties

• Melting Point: 194 °C
• Boiling Point: 199.42 °C at 760 mmHg
• Flash Point: 74.407 °C
• Appearance: off-white to pale yellowish solid
• Density: 1.553 g/cm³
• Vapor Pressure: 0.342mmHg at 25°C
• Refractive Index: 1.632
• Storage Temp.: Refrigerator
• Solubility: DMSO, Water
• PKA: 6.92±0.40(Predicted)
• CAS DataBase Reference: 6-Chloropyrimidin-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Chloropyrimidin-4(3H)-one(4765-77-9)
• EPA Substance Registry System: 6-Chloropyrimidin-4(3H)-one(4765-77-9)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-41-37/38-22
• Safety Statements: 22-26-36/37/39-39
• Hazardous Substances Data: 4765-77-9(Hazardous Substances Data)

Usage

Chemical Properties

Off-White to Pale Yellowish Solid

Uses

4-Chloro-6-hydroxypyrimidine (cas# 4765-77-9) is a compound useful in organic synthesis.

InChI:InChI=1/C4H3ClN2O/c5-3-1-4(8)7-2-6-3/h1-2H,(H,6,7,8)

Upstream product

• 26452-81-3 4-chloro-6-methoxy-pyrimidine 
• 1193-21-1 4,6-dichloropyrimidine 
• 77287-34-4 formamide 

Downstream Products

• 93118-59-3 4-(2,3-Dichlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-2-<<2-<(3,4-dihydro-4-oxopyrimidin-6-yl)amino>ethoxy>methyl>-1,4-dihydropyridine 
• 94295-28-0 6-(1-benzylhydrazino)-4(3H)-pyrimidinone 
• 94295-29-1 6-(1-methylhydrazino)pyrimidin-4(3H)-one 
• 26423-00-7 butyl-(6-chloro-pyrimidin-4-yl)-amine 
• 1159567-58-4 6-[4-(3-fluoro-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one 
• 1243253-47-5 6-chloro-3-(4-(2-hydroxy-2-methylpropoxy)-3-methoxyphenyl)-pyrimidin-4(3H)-one 
• 101079-62-3 6-chloro-3-methylpyrimidin-4(3H)-one 
• 130841-08-6 6-(4-chlorophenyl)-3H-pyrimidin-4-one 
• 99185-53-2 6-anilino-3H-pyrimidin-4-one 
• 3137-56-2 6-chloro-5-nitro-pyrimidin-4-ol 
• 88982-91-6 4,5-Dichlor-6-hydroxy-pyrimidin 
• 7038-75-7 6-Cyclopropyl-4-pyrimidinol 
• 6128-06-9 4-Hydroxy-6-methoxy-pyrimidin 
• 29939-37-5 4-hydrazino-6-hydroxypyrimidine 

Relevant articles and documents

Visible-Light-Induced Radical Difluoromethylation/Cyclization of Unactivated Alkenes: Access to CF2H-Substituted Quinazolinones

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FXIa blood coagulation factor inhibitor as well as pharmaceutical composition and application thereof

The invention relates to an FXIa blood coagulation factor inhibitor as well as a pharmaceutical composition and application thereof. Specifically, the invention discloses a compound shown as a formulaI or a pharmaceutically acceptable salt thereof. The invention also discloses a pharmaceutical composition containing the compound as shown in the formula I or pharmaceutically acceptable salt thereof, and application of the compound as shown in the formula I or pharmaceutically acceptable salt thereof. The compound disclosed by the invention is novel in structure and has good inhibitory activityon FXIa. .

BIARYL KINASE INHIBITORS

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INHIBITORS OF STEAROYL-COA DESATURASE

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PYRIMIDINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME

The present invention provides a pyrimidine derivative represented by the formula: wherein R1p and R1q are the same or different, and each represents (1)hydrogen, (2)halogen, (3) a C1-6alkyl group which may be substituted or (4) a C1-6alkoxy group, and so on, R2 is halogen, a C1-6alkyl group, cyano group, and so on, Ar is a phenyl group which may be substituted or is a condensed hetero ring which may be substituted, which has excellent selective herbicidal activity, and a herbicide containing the derivative.