501446-70-4

Basic information

• Product Name: 1-Piperidinecarboxylic acid, 4-[(4-bromophenyl)(phenylmethyl)amino]-, 1,1-dimethylethyl ester
• CAS NO: 501446-70-4
• Molecular Formula: C23H29BrN2O2
• Molecular Weight: 445.399
• Mol File: 501446-70-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-Piperidinecarboxylic acid, 4-[(4-bromophenyl)(phenylmethyl)amino]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidinecarboxylic acid, 4-[(4-bromophenyl)(phenylmethyl)amino]-, 1,1-dimethylethyl ester(501446-70-4)
• EPA Substance Registry System: 1-Piperidinecarboxylic acid, 4-[(4-bromophenyl)(phenylmethyl)amino]-, 1,1-dimethylethyl ester(501446-70-4)

Safety Data

• Hazardous Substances Data: 501446-70-4(Hazardous Substances Data)

Upstream product

• 443998-65-0 4-(4-Bromophenyl)amino-1-(tert-butoxycarbonyl)piperidine 
• 100-39-0 benzyl bromide 
• 106-40-1 4-bromo-aniline 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 

Downstream Products

• 501446-71-5 C₁₈H₂₁BrN₂ 

Relevant articles and documents

Design and synthesis of pyridin-2-ylmethylaminopiperidin-1-ylbutyl amide CCR5 antagonists that are potent inhibitors of M-tropic (R5) HIV-1 replication

A series of CCR5 antagonists were optimized for potent inhibition of R5 HIV-1 replication in peripheral blood mononuclear cells. Compounds that met acceptable ADME criteria, selectivity, human plasma protein binding, potency shift in the presence of α-glycoprotein were evaluated in rat and dog pharmacokinetics.