519058-41-4Relevant articles and documents
Design, Synthesis, and Biological Evaluation of Substituted 2-Cyclohexyl-4-phenyl-1H-imidazoles: Potent and Selective Neuropeptide Y Y5-Receptor Antagonists
Blum, Charles A.,Zheng, Xiaozhang,De Lombaert, Stéphane
, p. 2318 - 2325 (2007/10/03)
Antagonizing the robust stimulation of food intake by neuropeptide Y represents a new potential therapeutic approach for the treatment of obesity. Earlier pharmacological studies have pointed to the Y1 and Y5 receptors as the most likely mediators of the