5293-97-0

Basic information

• Product Name: 2,2'-DICHLOROBENZOPHENONE
• Synonyms: 2,2'-DICHLOROBENZOPHENONE;2,2''-DICHLOROBENZOPHENONE 98+%;Bis(2-chlorophenyl)methanone
• CAS NO: 5293-97-0
• Molecular Formula: C₁₃H₈Cl₂O
• Molecular Weight: 251.11
• Product Categories: Aromatic Benzophenones & Derivatives (substituted)
• Mol File: 5293-97-0.mol

Chemical Properties

• Melting Point: 52-53°C
• Boiling Point: 364.8 °C at 760 mmHg
• Flash Point: 154.2 °C
• Appearance: /
• Density: 1.311 g/cm³
• BRN: 2050630
• CAS DataBase Reference: 2,2'-DICHLOROBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2'-DICHLOROBENZOPHENONE(5293-97-0)
• EPA Substance Registry System: 2,2'-DICHLOROBENZOPHENONE(5293-97-0)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 5293-97-0(Hazardous Substances Data)

Usage

Uses

Used in Polymer and Coatings Industry:
2,2'-Dichlorobenzophenone is used as a photoinitiator for the curing process in the production of polymers and coatings. It facilitates the polymerization reaction under ultraviolet light, enhancing the efficiency and speed of the curing process.
Used in Pharmaceutical Industry:
2,2'-Dichlorobenzophenone serves as an intermediate in the synthesis of pharmaceuticals. Its unique chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Dye Industry:
In the dye industry, 2,2'-Dichlorobenzophenone is utilized as an intermediate for the synthesis of various dyes. Its chemical properties contribute to the creation of dyes with specific color characteristics and stability.
Used in Organic Compounds Synthesis:
2,2'-Dichlorobenzophenone is also used as an intermediate in the synthesis of other organic compounds. Its versatility in chemical reactions enables the production of a wide range of organic compounds for various applications.

Upstream product

• 3152-12-3 α-(hydroxy)-2-chloro-α-(2-chlorophenyl)benzeneacetic acid 
• 609-65-4 o-chlorobenzoyl chloride 
• 108-90-7 chlorobenzene 
• 89-98-5 2-chloro-benzaldehyde 
• 201230-82-2 carbon monoxide 
• 3900-89-8 2-Chlorobenzeneboronic acid 
• 694-80-4 2-bromo-1-chlorobenzene 
• 21854-95-5 2,2'-dichlorobenzil 
• 36692-27-0 2-chlorophenylmagnesium bromide 
• 615-41-8 2-iodochlorobenzene 
• 6335-15-5 2,2'-dichloro-benzhydrol 
• 32306-73-3 1,1'-methylenebis(2-chlorobenzene) 

Downstream Products

• 13102-33-5 2,2'-dimethoxybenzophenone 
• 6335-15-5 2,2'-dichloro-benzhydrol 
• 431063-11-5 2,2'-dichloro-diphenyldichloromethane 
• 117136-85-3 3-(2-acetoxymethylthiophenyl)-1,2-benzisothiazole 
• 117136-76-2 2,2'-bis methylthiobenzophenone oxime 
• 117136-84-2 3-(2-methylsulfinylphenyl)-1,2-benzisothiazole 
• 117136-83-1 3-(2-methylthiophenyl)-1,2-benzisothiazole 
• 117136-86-4 3-(2-mercaptophenyl)-1,2-benzisothiazole 

Relevant articles and documents

ACTION OF HETEROPOLY ACID AND RELATED OXIDES IN ACYLATION OF CHLOROBENZENE WITH o-CHLOROBENZOYL CHLORIDE

Heteropoly acids, MoO3, and calcined FeSO4 have been found to catalyze the acylation of chlorobenzene with o-chlorobenzoyl chloride.A kinetic study revealed that those catalysts are not active in their original forms, but the metal chlorides or metal complexes formed by reacting with chlorine are active for the acylation reaction.

Method for preparing symmetric diarylketone through catalytic oxidative carbonylation

The invention discloses a method for preparing symmetric diarylketone of a formula (I) as shown in the description. The method comprises the following steps: mixing arylboronic acid (II) (Ar-B(OH)2 (II)), a palladium catalyst, a promoter and an organic solvent in a reactor, introducing air and CO having a volume ratio of (7-19):1, reacting under the conditions of a pressure of 1-6 atm and a temperature of 30-80 DEG C for 8-16 hours, and performing after-treatment on the reaction solution, thereby obtaining the product symmetric diarylketone. According to the method disclosed by the invention,the air directly serves as an oxidizing agent to replace the O2 to be applied to oxidative carbonylation of the arylboronic acid, and the ratio of the air to CO is beyond an explosion limit. Therefore, the catalytic system is safe and economic. The palladium catalyst is small in dosage and simple in separation and can be recycled for several times. The method disclosed by the invention is mild inreaction condition, excellent in substrate suitability and high in yield.

Ligand-Free Palladium-Catalyzed Oxidative Carbonylative Homocoupling of Arylboron Reagents at Ambient Pressure

Arylboronic acids or potassium aryltrifluoroborates were readily oxidatively carbonylated to their corresponding diaryl ketones in high yields with high selectivities by ligand-free palladium-catalyzed homocoupling at atmospheric pressure. This novel method employs molecular oxygen or iodine as the oxidant and offers an attractive alternative to transition-metal-based oxidant systems.

Palladium-catalyzed oxidative carbonylation for the synthesis of symmetrical diaryl ketones at atmospheric co pressure

A mild and efficient synthesis of symmetrical diaryl ketones by palladium-catalyzed oxidative carbonylation of arylboronic acids with carbon monoxide at atmospheric pressure is reported. Georg Thieme Verlag Stuttgart New York.

Pd-catalyzed enantioselective C-H iodination: Asymmetric synthesis of chiral diarylmethylamines

An enantioselective C-H iodination reaction using a mono-N-benzoyl- protected amino acid has been developed for the synthesis of chiral diarylmethylamines. The reaction uses iodine as the sole oxidant and proceeds at ambient temperature and under air.

Method for acylation or sulphonylation of an aromatic compound

The present invention relates to a process for the acylation or sulphonylation of an aromatic compound. More particularly, the invention relates to a process for the acylation or sulphonylation of an activated or deactivated aromatic compound. The invention is applied to the preparation of aromatic ketones or sulphones. The process for the acylation or sulphonylation of an aromatic compound which consists in reacting at least one aromatic compound with an acylating or sulphonylating agent, in the presence of a Friedel-Crafts catalyst is characterized in that the acylation or sulphonylation reaction is carried out in liquid phase under microwave irradiation.

Carbonylative coupling of iodobenzene to benzophenone with [n-Bu4N][HFe(CO)4]

The reaction of Bu4N+[HFe(CO)4]- with iodobenzene in a biphasic medium (aqueous NaOH/benzene) under carbon monoxide (1 atm) affords benzophenone in 85% yield. Mechanistic investigations indicate that the reaction first involves an SET from [HFe(CO)4]- to Phi. Evidence for the generation of phenyl radicals and [(PhCO)Fe(CO)4]- species is presented. Separate experiments show that [(PhCO)Fe(CO)4]- does not react with Phi, but does with phenyl radicals, generated from Phi and Smh, leading to benzophenone. Eisevier,.

A new catalytic oxidation of diarylmethanes mediated by 2,2',3,3',5,5'- hexaphenyl-(1,1'-biphenyl)-4,4'-dioxyl

Diarylmethanes were catalytically oxidized with oxygen to benzophenones with a Cu(I)CI catalyst in butyronitrile as solvent in the presence of the mediating agent 2,2',3,3',5,5'-hexaphenyl-(1,1'-biphenyl)-4,4'-dioxyl 1, which was generated in situ from 2,2',3,3',5,5'-hexaphenyl-(1,1'-biphenyl)- 4-4'-diol 4.

Chromium(VI) Based Oxidants; IV. Zinc Chlorochromate Nonahydrate as an Efficient and Mild Oxidizing Agent

Zinc chlorochromate nonahydrate is an easily prepared and a cheap oxidizing agent for the oxidation of different types of hydroxy compounds, unsaturated hydrocarbons, and benzylic carbon hydrogen bonds at room temperature in dichloromethane.