53120-74-4

Basic information

• Product Name: 3,3-Dimethyl-1,5-pentanediol
• Synonyms: 3,3-Dimethyl-1,5-pentanediol;3,3-Dimethylpentane-1,5-diol
• CAS NO: 53120-74-4
• Molecular Formula: C₇H₁₆O₂
• Molecular Weight: 132.20074
• Mol File: 53120-74-4.mol
• Article Data: 25

Chemical Properties

• Melting Point: 44.24°C (estimate)
• Boiling Point: 233.16°C (rough estimate)
• Appearance: /
• Density: 0.9744 (rough estimate)
• Refractive Index: 1.4580
• Storage Temp.: 2-8°C
• PKA: 14.84±0.10(Predicted)
• CAS DataBase Reference: 3,3-Dimethyl-1,5-pentanediol(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-Dimethyl-1,5-pentanediol(53120-74-4)
• EPA Substance Registry System: 3,3-Dimethyl-1,5-pentanediol(53120-74-4)

Safety Data

• Hazardous Substances Data: 53120-74-4(Hazardous Substances Data)

Usage

General Description

3,3-Dimethyl-1,5-pentanediol is a chemical compound with the molecular formula C7H16O2. It is a clear, colorless liquid that is used as a solvent and in the production of various industrial and consumer products. It is also used as a component in the synthesis of certain polymers and as a plasticizer in some resin systems. Additionally, it is utilized in the formulation of personal care products, such as lotions and creams, due to its moisturizing properties. It is considered to have low toxicity and is generally considered to be safe for use in these applications.

Upstream product

• 4839-46-7 3,3-Dimethylglutaric acid 
• 17804-59-0 diethyl 3,3-dimethylglutarate 
• 4160-82-1 3,3-dimethylglutaric anhydride 
• 61193-04-2 3-(R,S),5-(R,S)-3,5-dicyano-4,4-dimethyl-2,6-dioxopiperidine 
• 110-94-1 1,5-pentanedioic acid 
• 53120-75-5 3,3-dimethylglutaryl chloride 

Downstream Products

• 37746-17-1 1,5-dibromo-3,3-dimethylpentane 
• 53120-76-6 3,3-dimethylpentane-1,5-diyl bis(4-methylbenzenesulfonate) 
• 139108-25-1 3,3-dimethyl-5-phenylmethoxy-1-pentanol 
• 7287-82-3 1-O-tolyl-ethanol 

Relevant articles and documents

Enantioselective Synthesis of N-Alkylamines through β-Amino C-H Functionalization Promoted by Cooperative Actions of B(C6F5)3and a Chiral Lewis Acid Co-Catalyst

We disclose a catalytic method for β-C(sp3)-H functionalization of N-alkylamines for the synthesis of enantiomerically enriched β-substituted amines, entities prevalent in pharmaceutical compounds and used to generate different families of chiral catalysts. We demonstrate that a catalyst system comprising of seemingly competitive Lewis acids, B(C6F5)3, and a chiral Mg- or Sc-based complex, promotes the highly enantioselective union of N-alkylamines and α,β-unsaturated compounds. An array of δ-amino carbonyl compounds was synthesized under redox-neutral conditions by enantioselective reaction of a N-alkylamine-derived enamine and an electrophile activated by the chiral Lewis acid co-catalyst. The utility of the approach is highlighted by late-stage β-C-H functionalization of bioactive amines. Investigations in regard to the mechanistic nuances of the catalytic processes are described.

3-(5-HYDROXY-1-OXOISOINDOLIN-2-YL)PIPERIDINE-2,6-DIONE DERIVATIVES AND USES THEREOF

The present disclosure provides a compound of Formula (I′): or a pharmaceutically acceptable salt, hydrate, solvate, prodrug, stereoisomer, or tautomer thereof, wherein Rx, X1, X2, and R1 are as defined herein, and methods of making and using same.

Compounds and Their Use in Treating Cancer

The specification generally relates to compounds of Formula (I): and pharmaceutically acceptable salts and prodrugs thereof, where R1, R4, R5, R6, R7, Linker, X, Y, A, G, D and E have any of the meanings defined herein. This specification also relates to the use of such compounds and pharmaceutically acceptable salts and prodrugs thereof in methods of treatment of the human or animal body, for example in prevention or treatment of cancer. This specification also relates to processes and intermediate compounds involved in the preparation of such compounds and to pharmaceutical compositions containing them.